The role of dosimetry audit in lung SBRT multi-centre clinical trials

被引：34

作者：

Clark, Catharine H. ^{[1
,2
,3
]}

Hurkmans, Coen W. ^{[4
,5
]}

Kry, Stephen F. ^{[6
,7
]}

机构：

[1] Royal Surrey Cty Hosp, Guildford, Surrey, England

[2] Natl Phys Lab, Teddington, Middx, England

[3] Mt Vernon Hosp, Natl Radiotherapy Trials QA RTTQA Grp, Northwood, Middx, England

[4] Catharina Hosp, Eindhoven, Netherlands

[5] European Org Res Treatment Canc, Brussels, Belgium

[6] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[7] Imaging & Radiat Oncol Core, Houston, TX USA

来源：

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS | 2017年 / 44卷

关键词：

Lung SBRT; Dosimetry audit; Clinical trials; VOLUME DELINEATION; QUALITY-ASSURANCE; DOSE CALCULATIONS; RADIOTHERAPY; IMPACT; CANCER; RADIOSURGERY; DELIVERY; QA;

D O I：

10.1016/j.ejmp.2017.04.003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Stereotactic Body Radiotherapy (SBRT) in the lung is a challenging technique which requires high quality clinical trials to answer the un-resolved clinical questions. Quality assurance of these clinical trials not only ensures the safety of the treatment of the participating patients but also minimises the variation in treatment, thus allowing the lowest number of patient treatments to answer the trial question. This review addresses the role of dosimetry audits in the quality assurance process and considers what can be done to ensure the highest accuracy of dose calculation and delivery and it's assessment in multi-centre trials. (C) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

引用

页码：171 / 176

页数：6

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