Complement Activation during Critical Illness: Current Findings and an Outlook in the Era of COVID-19

被引:13
作者
Bosmann, Markus [1 ,2 ]
机构
[1] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA
[2] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis, Mainz, Germany
关键词
D O I
10.1164/rccm.202005-1926ED
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:163 / 165
页数:4
相关论文
共 14 条
[1]   Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness [J].
Bain, William ;
Li, Huihua ;
van der Geest, Rick ;
Moore, Sara R. ;
Olonisakin, Tolani F. ;
Ahn, Brian ;
Papke, Erin ;
Moghbeli, Kaveh ;
DeSensi, Rebecca ;
Rapport, Sarah ;
Saul, Melissa ;
Hulver, Mei ;
Xiong, Zeyu ;
Mallampalli, Rama K. ;
Ray, Prabir ;
Morris, Alison ;
Ma, Lina ;
Doi, Yohei ;
Zhang, Yingze ;
Kitsios, Georgios D. ;
Kulkarni, Hrishikesh S. ;
McVerry, Bryan J. ;
Ferreira, Viviana P. ;
Nouraie, Mehdi ;
Lee, Janet S. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (02) :230-240
[2]  
Blanco-Melo D., 2020, SARS COV 2 LAUNCHES
[3]   Role of C3, C5 and Anaphylatoxin Receptors in Acute Lung Injury and in Sepsis [J].
Bosmann, Markus ;
Ward, Peter A. .
CURRENT TOPICS IN INNATE IMMUNITY II, 2012, 946 :147-159
[4]   Will Complement Inhibition Be the New Target in Treating COVID-19-Related Systemic Thrombosis? [J].
Campbell, Courtney M. ;
Kahwash, Rami .
CIRCULATION, 2020, 141 (22) :1739-1741
[5]   Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis [J].
Gralinski, Lisa E. ;
Sheahan, Timothy P. ;
Morrison, Thomas E. ;
Menachery, Vineet D. ;
Jensen, Kara ;
Leist, Sarah R. ;
Whitmore, Alan ;
Heise, Mark T. ;
Baric, Ralph S. .
MBIO, 2018, 9 (05)
[6]   Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV [J].
Jiang, Yuting ;
Zhao, Guangyu ;
Song, Nianping ;
Li, Pei ;
Chen, Yuehong ;
Guo, Yan ;
Li, Junfeng ;
Du, Lanying ;
Jiang, Shibo ;
Guo, Renfeng ;
Sun, Shihui ;
Zhou, Yusen .
EMERGING MICROBES & INFECTIONS, 2018, 7
[7]   Long-term treatment with eculizumab in paroxysmal nocturnal hemoglobinuria: sustained efficacy and improved survival [J].
Kelly, Richard J. ;
Hill, Anita ;
Arnold, Louise M. ;
Brooksbank, Gemma L. ;
Richards, Stephen J. ;
Cullen, Matthew ;
Mitchell, Lindsay D. ;
Cohen, Dena R. ;
Gregory, Walter M. ;
Hillmen, Peter .
BLOOD, 2011, 117 (25) :6786-6792
[8]  
Magro C, 2020, TRANSL RES, DOI [10.1016/j.trsl.2020.04.007-0., DOI 10.1016/J.TRSL.2020.04.007-0.]
[9]   The first case of COVID-19 treated with the complement C3 inhibitor AMY-101 [J].
Mastaglio, Sara ;
Ruggeri, Annalisa ;
Risitano, Antonio M. ;
Angelillo, Piera ;
Yancopoulou, Despina ;
Mastellos, Dimitrios C. ;
Huber-Lang, Markus ;
Piemontese, Simona ;
Assanelli, Andrea ;
Garlanda, Cecilia ;
Lambris, John D. ;
Ciceri, Fabio .
CLINICAL IMMUNOLOGY, 2020, 215
[10]   Eculizumab in Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder [J].
Pittock, S. J. ;
Berthele, A. ;
Fujihara, K. ;
Kim, H. J. ;
Levy, M. ;
Palace, J. ;
Nakashima, I. ;
Terzi, M. ;
Totolyan, N. ;
Viswanathan, S. ;
Wang, K. -C. ;
Pace, A. ;
Fujita, K. P. ;
Armstrong, R. ;
Wingerchuk, D. M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (07) :614-625