ACUTE KIDNEY INJURY IN 2011 Biomarkers are transforming our understanding of AKI

被引:22
作者
Chawla, Lakhmir S. [2 ]
Kellum, John A. [1 ]
机构
[1] Univ Pittsburgh, Dept Crit Care Med, Pittsburgh, PA 15261 USA
[2] George Washington Univ Hosp, Dept Anesthesiol & Crit Care Med, Washington, DC 20037 USA
基金
美国国家卫生研究院;
关键词
CRITICALLY-ILL PATIENTS; PROGRESSION; DISEASE; NGAL;
D O I
10.1038/nrneph.2011.216
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Acute kidney injury (AKI) is a syndrome of decreased renal function that is associated with an increased risk of death. Studies from 2011, particularly in the field of AKI biomarkers, have provided important insights into the diagnosis, prognosis, and treatment of AKI. These advances are now being brought to the bedside to improve diagnosis and treatment of AKI.
引用
收藏
页码:68 / 70
页数:3
相关论文
共 10 条
[1]   The severity of acute kidney injury predicts progression to chronic kidney disease [J].
Chawla, Lakhmir S. ;
Amdur, Richard L. ;
Amodeo, Susan ;
Kimmel, Paul L. ;
Palant, Carlos E. .
KIDNEY INTERNATIONAL, 2011, 79 (12) :1361-1369
[2]   MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3 [J].
Fasanaro, Pasquale ;
D'Alessandra, Yuri ;
Di Stefano, Valeria ;
Melchionna, Roberta ;
Romani, Sveva ;
Pompilio, Giulio ;
Capogrossi, Maurizio C. ;
Martelli, Fabio .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (23) :15878-15883
[3]   Epidemiology of Acute Kidney Injury [J].
Hoste, Eric A. J. ;
Kellum, John A. ;
Katz, Nevin M. ;
Rosner, Mitchell H. ;
Haase, Michael ;
Ronco, Claudio .
CARDIORENAL SYNDROMES IN CRITICAL CARE, 2010, 165 :1-8
[4]   The Magnitude of Acute Serum Creatinine Increase After Cardiac Surgery and the Risk of Chronic Kidney Disease, Progression of Kidney Disease, and Death [J].
Ishani, Areef ;
Nelson, David ;
Clothier, Barbara ;
Schult, Tamara ;
Nugent, Sean ;
Greer, Nancy ;
Slinin, Yelena ;
Ensrud, Kristine E. .
ARCHIVES OF INTERNAL MEDICINE, 2011, 171 (03) :226-233
[5]   Circulating miR-210 Predicts Survival in Critically Ill Patients with Acute Kidney Injury [J].
Lorenzen, Johan M. ;
Kielstein, Jan T. ;
Hafer, Carsten ;
Gupta, Shashi K. ;
Kuempers, Philipp ;
Faulhaber-Walter, Robert ;
Haller, Hermann ;
Fliser, Danilo ;
Thum, Thomas .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 6 (07) :1540-1546
[6]   Oliguria is an early predictor of higher mortality in critically ill patients [J].
Macedo, Etienne ;
Malhotra, Rakesh ;
Bouchard, Josee ;
Wynn, Susan K. ;
Mehta, Ravindra L. .
KIDNEY INTERNATIONAL, 2011, 80 (07) :760-767
[7]   MCP-1 Gene Activation Marks Acute Kidney Injury [J].
Munshi, Raj ;
Johnson, Ali ;
Siew, Edward D. ;
Ikizler, T. Alp ;
Ware, Lorraine B. ;
Wurfel, Mark M. ;
Himmelfarb, Jonathan ;
Zager, Richard A. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 22 (01) :165-175
[8]   The Ngal reporter mouse detects the response of the kidney to injury in real time [J].
Paragas, Neal ;
Qiu, Andong ;
Zhang, Qingyin ;
Samstein, Benjamin ;
Deng, Shi-Xian ;
Schmidt-Ott, Kai M. ;
Viltard, Melanie ;
Yu, Wenqiang ;
Forster, Catherine S. ;
Gong, Gangli ;
Liu, Yidong ;
Kulkarni, Ritwij ;
Mori, Kiyoshi ;
Kalandadze, Avtandil ;
Ratner, Adam J. ;
Devarajan, Prasad ;
Landry, Donald W. ;
D'Agati, Vivette ;
Lin, Chyuan-Sheng ;
Barasch, Jonathan .
NATURE MEDICINE, 2011, 17 (02) :216-U113
[9]   Neutrophil gelatinase-associated lipocalin (NGAL) as a Biomarker for Early Acute Kidney Injury [J].
Shemin, Douglas ;
Dworkin, Lance D. .
CRITICAL CARE CLINICS, 2011, 27 (02) :379-+
[10]   Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia [J].
Srisawat, Nattachai ;
Murugan, Raghavan ;
Lee, Minjae ;
Kong, Lan ;
Carter, Melinda ;
Angus, Derek C. ;
Kellum, John A. .
KIDNEY INTERNATIONAL, 2011, 80 (05) :545-552