Cap-Snatching Leads to Novel Viral Proteins

被引:4
作者
Russell, Alistair B. [1 ]
机构
[1] Univ Calif San Diego, Dept Biol, San Diego, CA 92103 USA
关键词
D O I
10.1016/j.cell.2020.05.044
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Some negative-sense RNA viruses prime mRNA transcription using host 50 cap sequences, usurping host translational machinery and evading antiviral surveillance. In this issue of Cell, Ho et al. identify an additional consequence of this viral strategy: the acquisition of upstream start codons from host-derived sequences and subsequent translation of novel viral products.
引用
收藏
页码:1450 / 1451
页数:2
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