Nitropyrazoles 14. Synthesis of 1,3,4-trinitropyrazole and its behavior in the nucleophilic substitution reactions. General method of synthesis of 5-substituted 3,4-dinitropyrazoles

被引：21

作者：

Dalinger, I. L. ^{[1
]}

Cherkasova, T. I. ^{[1
]}

Popova, G. P. ^{[1
]}

Shkineva, T. K. ^{[1
]}

Vatsadze, I. A. ^{[1
]}

Shevelev, S. A. ^{[1
]}

Kanishchev, M. I. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2009年 / 58卷 / 02期

关键词：

pyrazole; nitropyrazole; N-nitration; nitro group; cine-substitution; nucleophylic substitution; C-NUCLEOSIDE; CINE-SUBSTITUTION; 1,4-DINITROPYRAZOLES; PYRAZOLES; FORMYCIN; ANALOG;

D O I：

10.1007/s11172-010-0024-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

For the first time pyrazole containing three nitro groups in the pyrazole cycle, viz., 1,3,4-trinitropyrazole, was obtained by N-nitration of 3,4-dinitropyrazole. 1,3,4- Trinitropyrazole enters the cine-substitution reaction of N-nitro group under the action of O-, N-, and C-nucleophyls under mild conditions. Thus, general method of synthesis of 5-substituted 3,4-dinitropyrazoles containing free NH fragment was worked out.

引用

页码：410 / 413

页数：4

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