Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry

被引：141

作者：

Rijkers, DTS ^{[1
]}

van Esse, GW ^{[1
]}

Merkx, R ^{[1
]}

Brouwer, AJ ^{[1
]}

Jacobs, HJF ^{[1
]}

Pieters, RJ ^{[1
]}

Liskamp, RMJ ^{[1
]}

机构：

[1] Univ Utrecht, Fac Pharmaceut Sci, Dept Med Chem, Utrecht Inst Pharmaceut Sci, NL-3508 TB Utrecht, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 36期

关键词：

D O I：

10.1039/b507975f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multivalent dendrimeric peptides were synthesized via a microwave-assisted Huisgen 1,3-dipolar cycloaddition between azido peptides and dendrimeric alkynes in yields ranging from 46 to 96%.

引用

页码：4581 / 4583

页数：3

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