Efficacy and safety of low-dose corticosteroid with azathioprine in the treatment of elderly-onset IgA vasculitis with nephritis

被引：2

作者：

Sugimoto, Hikaru ^{[1
]}

Yamaguchi, Yasuko ^{[1
]}

Yumura, Wako ^{[1
]}

Takei, Takashi ^{[1
]}

机构：

[1] Tokyo Metropolitan Geriatr Hosp, Dept Nephrol, Itabashi Ku, Tokyo, Japan

来源：

BMJ CASE REPORTS | 2021年 / 14卷 / 06期

关键词：

nephrotic syndrome; geriatric medicine; vasculitis; HENOCH-SCHONLEIN PURPURA; METHYLPREDNISOLONE PULSE; DOUBLE-BLIND; THERAPY; NEPHROPATHY; PREDNISONE; DIAGNOSIS; DISEASE;

D O I：

10.1136/bcr-2020-241422

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The diagnosis of elderly-onset IgA vasculitis (IgAV) and its prognosis can be difficult to ascertain because of its rarity and the frequent presence of comorbidities. Furthermore, the treatment of elderly-onset IgAV remains controversial. We report a case of IgAV in an 87-year-old patient. Renal involvement was detected early during the IgAV follow-up. He was treated with low-dose corticosteroid and azathioprine, which led to a complete remission without any adverse effects. This suggests that precise intervention with early diagnosis and careful renal follow-up may prevent renal failure and that low-dose steroids with azathioprine can be an effective treatment for elderly-onset IgAV with nephritis.

引用

页数：6

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