Development of a Universal Influenza Vaccine

被引：69

作者：

Estrada, Leonardo D. ^{[1
]}

Schultz-Cherry, Stacey ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Infect Dis, Memphis, TN 38105 USA

来源：

JOURNAL OF IMMUNOLOGY | 2019年 / 202卷 / 02期

关键词：

INHIBITION ANTIBODY-TITERS; A VIRUS HEMAGGLUTININ; LINKED LECTIN ASSAY; T-CELL RESPONSES; TEMPERATURE SENSITIVITY; NEURAMINIDASE ANTIBODY; EXTRACELLULAR DOMAIN; IMMUNE-RESPONSES; UNITED-STATES; M2; PROTEIN;

D O I：

10.4049/jimmunol.1801054

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The severity of the 2017-18 influenza season, combined with the low efficacy for some vaccine components, highlights the need to improve our current seasonal influenza vaccine. Thus, the National Institute of Allergy and Infectious Diseases recently announced a strategic plan to improve current influenza vaccines and eventually develop a "universal" influenza vaccine. This review will highlight the many different strategies being undertaken in pursuit of this goal and the exciting advances made by the influenza community. There is no doubt that an improved influenza vaccine is on the horizon.

引用

页码：392 / 398

页数：7

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