A multicenter randomized controlled trial of two group education programs for fatigue in multiple sclerosis: Long-term (12-month) follow-up at one site

被引：5
|
作者：
Hugos, Cinda L. [1 ]
Cameron, Michelle H. [1 ]
Chen, Zunqiu [2 ]
Chen, Yiyi [2 ]
Bourdette, Dennis [1 ]
机构：
[1] Oregon Hlth & Sci Univ, VA Portland Hlth Care Syst, Portland, OR 97201 USA
[2] Oregon Hlth & Sci Univ, OHSU PSU Sch Publ Hlth, OHSU Biostat Design Program, Portland, OR 97201 USA
来源：
MULTIPLE SCLEROSIS JOURNAL | 2019年 / 25卷 / 06期
关键词：
Multiple sclerosis; fatigue; rehabilitation; self-care; clinical trial; symptom management;
D O I：
10.1177/1352458518775920
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background: A four-site RCT of Fatigue: Take Control (FTC), a multicomponent group program, found no significant differences from a control program, MS: Take Control (MSTC), in fatigue on the Modified Fatigue Impact Scale (MFIS) through 6 months. Objective: Assess FTC for a delayed effect on fatigue. Methods: Of 78 subjects at one site, 74 randomized to FTC or MSTC completed the MFIS at 12 months. Results: Compared to baseline, FTC produced greater improvements in MFIS scores than MSTC (FTC -8.9 (confidence interval (CI): 32.2, 45), MSTC -2.5 (CI 39.6, 47.7), p = 0.03) at 12 months. Conclusion: The delayed effect of FTC on fatigue suggests the need for longer follow-up when assessing interventions for fatigue.
引用
收藏
页码：871 / 875
页数：5
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