A genetic developmental model of iron deficiency: Biological aspects

被引：38

作者：

Morse, AC

Beard, JL

Jones, BC

机构：

[1] Penn State Univ, Coll Hlth & Human Dev, Dept Biobehav Hlth, University Pk, PA 16802 USA

[2] Penn State Univ, Coll Hlth & Human Dev, Dept Nutr, University Pk, PA 16802 USA

来源：

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE | 1999年 / 220卷 / 03期

关键词：

D O I：

10.1046/j.1525-1373.1999.d01-22.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Numerous studies have demonstrated the negative impact of iron deficiency on growth and development. The present study expands on the published literature by exploring the role of genetics and developmental timing on the impact of iron deficiency on development in two strains of mice. Growth rates, organ weights, and hematological responses to an iron-deficient diet differed by strain and sex, The results from this study provided novel insight into iron metabolism and the impact of iron deficiency in C57 and DBA strains of mice. Future studies should continue to examine the contributions of both genetics and sex to the development of iron deficiency.

引用

页码：147 / 152

页数：6

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