High sensitivity photonic crystal biosensor incorporating nanorod structures for enhanced surface area

被引：88

作者：

Zhang, Wei ^{[1
]}

Ganesh, Nikhil ^{[1
]}

Block, Ian D. ^{[1
]}

Cunningham, Brian T. ^{[1
]}

机构：

[1] Univ Illinois, Micro & Nanotechnol Lab, Nano Sensors Grp, Urbana, IL 61801 USA

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2008年 / 131卷 / 01期

基金：

美国国家科学基金会;

关键词：

biosensor; surface area; photonic crystal; nanostructure; sensitivity; glancing angle deposition;

D O I：

10.1016/j.snb.2007.11.017

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The surface area of a photonic crystal biosensor is greatly enhanced through the incorporation of a porous TiO2 film possessing the structure of nanorods into the device. The film is deposited by the glancing angle deposition technique in an e-beam evaporation system. The sensitivity of high surface area sensors is compared with sensors without the high surface area coating. Results for detection of polymer films, large proteins and small molecules indicate up to a four-fold enhancement of detected adsorbed mass density. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：279 / 284

页数：6

共 35 条

[1] Integration of nanostructured materials with MEMS microhotplate platforms to enhance chemical sensor performance [J].

Benkstein, Kurt D. ;

Martinez, Carlos J. ;

Li, Guofeng ;

Meier, Douglas C. ;

Montgomery, Christopher B. ;

Semancik, Steve .

JOURNAL OF NANOPARTICLE RESEARCH, 2006, 8 (06) :809-822

[2] Photonic crystal optical biosensor incorporating structured low-index porous dielectric [J].

Block, Ian D. ;

Chan, Leo L. ;

Cunningham, Brian T. .

SENSORS AND ACTUATORS B-CHEMICAL, 2006, 120 (01) :187-193

[3] Nanoscale silicon microcavities for biosensing [J].

Chan, S ;

Li, Y ;

Rothberg, LJ ;

Miller, BL ;

Fauchet, PM .

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2001, 15 (1-2) :277-282

[4] Aligned silver nanorod arrays produce high sensitivity surface-enhanced Raman spectroscopy substrates [J].

Chaney, SB ;

Shanmukh, S ;

Dluhy, RA ;

Zhao, YP .

APPLIED PHYSICS LETTERS, 2005, 87 (03)

[5] Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity [J].

Chow, E ;

Grot, A ;

Mirkarimi, LW ;

Sigalas, M ;

Girolami, G .

OPTICS LETTERS, 2004, 29 (10) :1093-1095

[6] A plastic colorimetric resonant optical biosensor for multiparallel detection of label-free biochemical interactions [J].

Cunningham, B ;

Lin, B ;

Qiu, J ;

Li, P ;

Pepper, J ;

Hugh, B .

SENSORS AND ACTUATORS B-CHEMICAL, 2002, 85 (03) :219-226

[7] Colorimetric resonant reflection as a direct biochemical assay technique [J].

Cunningham, B ;

Li, P ;

Lin, B ;

Pepper, J .

SENSORS AND ACTUATORS B-CHEMICAL, 2002, 81 (2-3) :316-328

[8] Microplate-based, label-free detection of biomolecular interactions: applications in proteomics [J].

Cunningham, Brian T. ;

Laing, Lance .

EXPERT REVIEW OF PROTEOMICS, 2006, 3 (03) :271-281

[9] Label-free assays on the BIND system [J].

Cunningham, BT ;

Li, P ;

Schulz, S ;

Lin, B ;

Baird, C ;

Gerstenmaier, J ;

Genick, C ;

Wang, F ;

Fine, E ;

Laing, L .

JOURNAL OF BIOMOLECULAR SCREENING, 2004, 9 (06) :481-490

[10] Glutamine-binding protein from Escherichia coli specifically binds a wheat gliadin peptide allowing the design of a new porous silicon-based optical biosensor [J].

De Stefano, L ;

Rossi, M ;

Staiano, M ;

Mamone, G ;

Parracino, A ;

Rotiroti, L ;

Rendina, I ;

Rossi, M ;

D'Auria, S .

JOURNAL OF PROTEOME RESEARCH, 2006, 5 (05) :1241-1245

← 1 2 3 4 →