Long-term outcomes in patients undergoing percutaneous coronary intervention with drug-eluting stents

被引：0

作者：

Rossini, Roberta ^{[1
]}

Musumeci, Giuseppe ^{[2
]}

Aprile, Alessandro ^{[3
]}

Valsecchi, Orazio ^{[2
]}

机构：

[1] Osped Riuniti Bergamo, Dipartimento Cardiovasc, USC Cardiol, I-24122 Bergamo, Italy

[2] Osped Riuniti Bergamo, Dipartimento Cardiovasc, USC Cardiol Diagnost Interventist 2, I-24122 Bergamo, Italy

[3] Policlin Modena, Lab Emodinam, Div Cardiol, Modena, Italy

来源：

EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH | 2010年 / 10卷 / 01期

关键词：

bare-metal stent; drug-eluting stent; percutaneous coronary intervention; stent thrombosis; target-lesion revascularization; BARE-METAL STENTS; AMERICAN-HEART-ASSOCIATION; DUAL ANTIPLATELET THERAPY; COLLEGE-OF-CARDIOLOGY; CLINICAL FOLLOW-UP; ARTERY-DISEASE; POOLED ANALYSIS; CARDIOVASCULAR ANGIOGRAPHY; PREMATURE DISCONTINUATION; DENTAL-ASSOCIATION;

D O I：

10.1586/ERP.10.1

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Drug-eluting stents substantially reduce restenosis compared with bare-metal stents and represent a significant advance in percutaneous coronary interventions. Accordingly, drug-eluting stents have been rapidly adopted into practice and are currently used in the vast majority of complex percutaneous coronary procedures. However, in the last 2 years, concerns have been raised regarding their long-term safety, especially regarding the risk of late and very-late stent thrombosis. Delayed endothelial coverage after drug-eluting stent implantation is thought to prolong the window of vulnerability to stent thrombosis, which requires a prolonged dual antiplatelet therapy. Recent registry studies and meta-analyses seem to have provided reassuring results regarding the long-term rates of death and myocardial infarction associated with the use of drug-eluting stents compared with bare-metal stents. However, data are not consistent and concerns remain.

引用

页码：49 / 61

页数：13

共 86 条

[1] Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment [J].

Airoldi, Flavio ;

Colombo, Antonio ;

Morici, Nuccia ;

Latib, Azeem ;

Cosgrave, John ;

Buellesfeld, Lutz ;

Bonizzoni, Erminio ;

Carlino, Mauro ;

Gerckens, Ulrich ;

Godino, Cosmo ;

Melzi, Gloria ;

Michev, Iassen ;

Montorfano, Matteo ;

Sangiorgi, Giuseppe Massimo ;

Qasim, Asif ;

Chieffo, Alaide ;

Briguori, Carlo ;

Grube, Eberhard .

CIRCULATION, 2007, 116 (07) :745-754

[2]

[Anonymous], ADV CRYOGEN ENG, DOI DOI 10.1007/978-1-4757-9047-4_77

[3] Genous™ endothelial progenitor cell capturing stent vs. the Taxus Liberte stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single-centre, pilot study [J].

Beijk, Marcel A. M. ;

Klomp, Margo ;

Verouden, Niels J. W. ;

van Geloven, Nan ;

Koch, Karel T. ;

Henriques, Jose P. S. ;

Baan, Jan ;

Vis, Marije M. ;

Scheunhage, Esther ;

Piek, Jan J. ;

Tijssen, Jan G. P. ;

de Winter, Robbert J. .

EUROPEAN HEART JOURNAL, 2010, 31 (09) :1055-1064

[4] Intracoronary Optical Coherence Tomography: A Comprehensive Review Clinical and Research Applications [J].

Bezerra, Hiram G. ;

Costa, Marco A. ;

Guagliumi, Giulio ;

Rollins, Andrew M. ;

Simon, Daniel I. .

JACC-CARDIOVASCULAR INTERVENTIONS, 2009, 2 (11) :1035-1046

[5] Optimal medical therapy with or without PCI for stable coronary disease [J].

Boden, William E. ;

O'Rourke, Robert A. ;

Teo, Koon K. ;

Hartigan, Pamela M. ;

Maron, David J. ;

Kostuk, William J. ;

Knudtson, Merril ;

Dada, Marcin ;

Casperson, Paul ;

Harris, Crystal L. ;

Chaitman, Bernard R. ;

Shaw, Leslee ;

Gosselin, Gilbert ;

Nawaz, Shah ;

Title, Lawrence M. ;

Gau, Gerald ;

Blaustein, Alvin S. ;

Booth, David C. ;

Bates, Eric R. ;

Spertus, John A. ;

Berman, Daniel S. ;

Mancini, G. B. John ;

Weintraub, William S. ;

Boden, W. ;

O'Rourke, R. ;

Teo, K. ;

Hartigan, P. ;

Weintraub, W. ;

Maron, D. ;

Mancini, J. ;

Weintraub, W. ;

Boden, W. ;

O'Rourke, R. ;

Teo, K. ;

Hartigan, P. ;

Knudtson, M. ;

Maron, D. ;

Bates, E. ;

Blaustein, A. ;

Booth, D. ;

Carere, R. ;

Ellis, S. ;

Gosselin, G. ;

Gau, G. ;

Jacobs, A. ;

King, S., III ;

Kostuk, W. ;

Harris, C. ;

Spertus, J. ;

Peduzzi, P. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (15) :1503-1516

[6] Drug-eluting stents: a comprehensive appraisal [J].

Butt, Mehmood ;

Connolly, Derek ;

Lip, Gregory Y. H. .

FUTURE CARDIOLOGY, 2009, 5 (02) :141-157

[7] 5-Year Clinical Outcomes After Sirolimus-Eluting Stent Implantation Insights From a Patient-Level Pooled Analysis of 4 Randomized Trials Comparing Sirolimus-Eluting Stents With Bare-Metal Stents [J].

Caixeta, Adriano ;

Leon, Martin B. ;

Lansky, Alexandra J. ;

Nikolsky, Eugenia ;

Aoki, Jiro ;

Moses, Jeffrey W. ;

Schofer, Joachim ;

Morice, Marie-Claude ;

Schampaert, Erick ;

Kirtane, Ajay J. ;

Popma, Jeffrey J. ;

Parise, Helen ;

Fahy, Martin ;

Mehran, Roxana .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (10) :894-902

[8] Stent thrombosis late after implantation of first-generation drug-eluting stents - A cause for concern [J].

Camenzind, Edoardo ;

Steg, P. Gabriel ;

Wijns, William .

CIRCULATION, 2007, 115 (11) :1440-1455

[9]

Chevalier Bernard, 2007, EuroIntervention, V2, P426

[10] Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice:: data from a large two-institutional cohort study [J].

Daemen, Joost ;

Wenaweser, Peter ;

Tsuchida, Keiichi ;

Abrecht, Linda ;

Sophia, Vaina ;

Morger, Cyrill ;

Kukreja, Neville ;

Jueni, Peter ;

Sianos, Georgios ;

Hellige, Gerrit ;

van Domburg, Ron T. ;

Hess, Otto M. ;

Boersma, Eric ;

Meier, Bernhard ;

Windecker, Stephan ;

Serruys, Patrick W. .

LANCET, 2007, 369 (9562) :667-678

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