Bifunctional N-Acyl-Aminophosphine-Catalyzed Asymmetric [4+2] Cycloadditions of Allenoates and Imines

被引：99

作者：

Xiao, Hua ^{[1
]}

Chai, Zhuo ^{[2
]}

Wang, Hai-Feng ^{[2
]}

Wang, Xiao-Wei ^{[2
]}

Cao, Dong-Dong ^{[1
]}

Liu, Wen ^{[1
]}

Lu, Ying-Peng ^{[2
]}

Yang, Ying-Quan ^{[1
]}

Zhao, Gang ^{[1
,2
]}

机构：

[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Lab Modern Synthet Chem, Shanghai 200032, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 38期

基金：

中国国家自然科学基金;

关键词：

aminophosphines; asymmetric catalysis; bifunctional catalyst; cycloaddition; organocatalysis; HIGHLY FUNCTIONALIZED TETRAHYDROPYRIDINES; ELECTRON-DEFICIENT OLEFINS; MODIFIED ALLYLIC COMPOUNDS; PHOSPHORUS YLIDE REACTION; BAYLIS-HILLMAN REACTIONS; DIELS-ALDER REACTIONS; 3+2 ANNULATION; DIASTEREOSELECTIVE SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; PHOSPHINE ORGANOCATALYSIS;

D O I：

10.1002/chem.201100850

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Try bifunctional aminophosphines! An asymmetric organocatalytic [4+2] cycloaddition between α-substituted allenoates and tosylaldimines using bifunctional N-acyl aminophosphine catalysts was described (see scheme). This operationally simple catalytic system could provide valuable complementary results to those of the monodentate phosphine system. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10562 / 10565

页数：4