The asymmetric transfer hydrogenation of benzoylpyridine: preparation and crystal structure of chiral heterocyclic Schiff base ligands

被引：3

作者：

Zhang, Yu-Mei ^{[1
]}

Zhang, Hong-Li ^{[1
]}

Liu, Peng ^{[1
]}

机构：

[1] Hebei Univ Sci & Technol, Coll Sci, Shijiazhuang 050018, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2011年 / 01期

关键词：

asymmetric transfer hydrogenation; Schiff base; synthesis; chiral; DIASTEREOSELECTIVE ADDITION; COMPLEXES; AMINES; IMINE;

D O I：

10.3184/174751911X556738

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two optically active heterocyclic imine ligands 3 (3a and 3b) have been synthesised for the iridium catalysed asymmetric transfer hydrogenation of 4-benzoylpyridine. 3b was characterised by single crystal X-ray diffraction analysis. The two ligands (3a and 3b) were applied to Ir-catalysed asymmetric transfer hydrogenation of 4-benzoylpyridine using 2-propanol as a source of hydrogen. The results showed that the corresponding chiral alcohol could be obtained with moderate yield and enantioselectivity at an optimum temperature.

引用

页码：26 / 28

页数：3

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