Saliva sampling: Methods and devices. An overview

被引:203
作者
Bellagambi, Francesca G. [1 ,2 ]
Lomonaco, Tommaso [2 ]
Salvo, Pietro [3 ]
Vivaldi, Federico [2 ]
Hangouet, Marie [1 ]
Ghimenti, Silvia [2 ]
Biagini, Denise [2 ]
Di Francesco, Fabio [2 ]
Fuoco, Roger [2 ]
Errachid, Abdelhamid [1 ]
机构
[1] Univ Claude Bernard Lyon 1, Inst Sci Analyt, 43 Blvd 11 Novembre 1918, F-69100 Lyon, France
[2] Univ Pisa, Dept Chem & Ind Chem, Via Giuseppe Moruzzi 13, I-56124 Pisa, Italy
[3] Inst Clin Physiol, Natl Res Council, Lab Bioinformat, Via Giuseppe Moruzzi 1, I-56124 Pisa, Italy
关键词
Saliva; Saliva analysis; Saliva sampling methods; Saliva sampling devices; Saliva composition; Salivary biomarkers; SOLID-PHASE MICROEXTRACTION; SQUAMOUS-CELL CARCINOMA; NECROSIS-FACTOR-ALPHA; ORAL LICHEN-PLANUS; FLOW-RATE; COLLECTION DEVICES; TNF-ALPHA; DIAGNOSTIC UTILITY; ILLICIT DRUGS; WHOLE SALIVA;
D O I
10.1016/j.trac.2019.115781
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The continuous exchange of chemicals with blood and the non-invasive collection make saliva an interesting specimen for clinical applications, from the detection of biomarkers to the new eomic sciences in medicine. However, saliva sampling is challenging because the suitability of the collection method for the analyte of interest is either poorly investigated or, more often, not mentioned at all in most publications. This review reports a critical evaluation of the most common procedures for saliva sampling and a description of the off-the-shelf sampling devices. Their suitability for bioanalytical applications and salivary biomarkers detection, e.g. representativeness of the sample, sampling feasibility, analyte recovery, and sample amount, is discussed. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页数:15
相关论文
共 173 条
[1]   Dried saliva spot as a sampling technique for saliva samples [J].
Abdel-Rehim, Abbi ;
Abdel-Rehim, Mohamed .
BIOMEDICAL CHROMATOGRAPHY, 2014, 28 (06) :875-877
[2]   The distribution of oral mucosal pH values in healthy saliva secretors [J].
Aframian, D. J. ;
Davidowitz, T. ;
Benoliel, R. .
ORAL DISEASES, 2006, 12 (04) :420-423
[3]  
Al-Ghurabei BH., 2011, J Fac Med Baghdad, V53, P207
[4]  
[Anonymous], J VIS EXP
[5]  
[Anonymous], OPEN FORUM INFECT DI
[6]  
[Anonymous], 2011, ACAD J CANC RES
[7]  
[Anonymous], JAP J PHYSL PSYCHOL
[8]  
[Anonymous], J BREATH RES
[9]  
[Anonymous], 2017, COMP CLIN PATHOL, DOI DOI 10.1007/s00580-017-2415-5
[10]   Review: The physiology of saliva and transfer of drugs into saliva [J].
Aps, JKM ;
Martens, LC .
FORENSIC SCIENCE INTERNATIONAL, 2005, 150 (2-3) :119-131