ANTIMICROBIAL ACTIVITY OF Bi(III) COMPLEXES WITH SOME SULPHONIC ACIDS

被引:1
作者
Alexandar, Irina [1 ]
Kaloyanov, Nikolay [2 ]
Parvanova, Veneta [3 ]
Girginov, Christian [4 ]
Zahariev, Alexander [5 ]
机构
[1] Bulgarian Acad Sci, Inst Mol Biol, Akad G Bonchev St,Bl 21, Sofia 1113, Bulgaria
[2] Univ Chem Technol & Met, Dept Organ Chem, 8 St Kliment Ohridski Blvd, Sofia 1756, Bulgaria
[3] Univ Chem Technol & Met, Dept Inorgan Chem, 8 St Kliment Ohridski Blvd, Sofia 1756, Bulgaria
[4] Univ Chem Technol & Met, Dept Phys Chem, 8 St Kliment Ohridski Blvd, Sofia 1756, Bulgaria
[5] Tech Univ Sofia, Dept Chem, 8 St Kliment Ohridski Blvd, Sofia 1000, Bulgaria
来源
COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES | 2021年 / 74卷 / 08期
关键词
Bi(III) complexes; sulphonic acids; antibacterial activity; BISMUTH;
D O I
10.7546/CRABS.2021.08.06
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Antimicrobial susceptibility and microbial resistance are investigated for three Bi(III) complexes: [Bi604(OH)4](NH2S03)6 (KZ1), [Bi606(OH)2](NH2 C6H4S03)4 (KZ2) and [Bi606(OH)3] (C7H7S03)3 (KZ3), which have been previously synthesized. Prokaryotic cells Escherichia coli (ATCC 47093 and ATCC 25922) and Staphylococcus aureus (ATCC 29213) as well as yeast Saccharomyces cerevisiae (ATCC 200060, diploid, wild type) are used. Results demonstrate that KZ1, KZ2 and KZ3 complexes inhibit effectively the growth of bacteria but not of the yeast. Moreover, the investigation proves that S. aureus reveals the highest sensitivity towards KZ1. It is noteworthy that KZ1 and KZ3 reveal higher activity than ampicillin. The antibacterial activity of three complexes is similar to that of kanamycin against the examined strains.
引用
收藏
页码:1155 / 1160
页数:6
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