Gold nanoparticles and cancer: Detection, diagnosis and therapy

被引：58

作者：

Medici, Serenella ^{[1
]}

Peana, Massimiliano ^{[1
]}

Coradduzza, Donatella ^{[2
]}

Zoroddu, Maria Antonietta ^{[1
]}

机构：

[1] Univ Sassari, Dept Chem & Pharm, Sassari, Italy

[2] Univ Sassari, Dept Biomed Sci, Sassari, Italy

来源：

SEMINARS IN CANCER BIOLOGY | 2021年 / 76卷

关键词：

Gold nanoparticles; Cancer; AuNPs; Detection; Diagnosis; Therapy; TARGETED DRUG-DELIVERY; SIRNA DELIVERY; CURCUMIN; TOXICITY; CELLS; GENE; PH; CYTOTOXICITY; CHEMOTHERAPY; PROTEINS;

D O I：

10.1016/j.semcancer.2021.06.017

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gold nanoparticles (AuNPS) represent one of the most studied classes of nanomaterials for biomedical applications, especially in the field of cancer research. In fact, due to their unique properties and high versatility, they can be exploited under all aspects connected to cancer management, from early detection to diagnosis and treatment. AuNPs have thus been tested with amazing results as biosensors, contrast agents, therapeutics. Their importance as potent theranostics is undoubted, but the translation to clinical practice has been hampered by a series of aspects, such as the unclear toxicity in humans and the lack of thorough studies on reliable animal models. Still, their potential action is so appealing and the results so impressive that an outstanding number of papers is being published every year, with the consequence that any review on this topic becomes obsolete within a few months. Here we would like to report the latest findings on AuNPs research addressing all their functions as theranostic agents.

引用

页码：27 / 37

页数：11

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[31] Dragon fruit extract capped gold nanoparticles: Synthesis and their differential cytotoxicity effect on breast cancer cells [J].