Variable-temperature and variable-pressure studies of small-molecule organic crystals

被引：47
作者：
Boldyreva, EV [1 ]
Drebushchak, TN
Shakhtshneider, TP
Sowa, H
Ahsbahs, H
Goryainov, SV
Ivashevskaya, SN
Kolesnik, EN
Drebushchak, VA
Burgina, EB
机构：
[1] Novosibirsk State Univ, REC Mol Design & Ecologically Safe Technol 008, Pirogova 2, Novosibirsk 630090, Russia
[2] RAS, SB, Inst Solid State Chem, Novosibirsk, Russia
[3] Univ Marburg, D-35032 Marburg, Germany
[4] RAS, SB, Inst Mineral & Petrog, Novosibirsk, Russia
[5] RAS, Karelian Sci Ctr, Inst Geol, Petrozavodsk, Russia
[6] RAS, SB, Boreskov Inst Catalysis, Novosibirsk, Russia
来源：
ARKIVOC | 2004年
关键词：
hydrogen bonds; high pressure; amino acids; polymorphs; phase transitions;
D O I：
10.3998/ark.5550190.0005.c10
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several examples of the comparative variable- temperature and variable- pressure studies of the small- molecule organic crystals are discussed. Selected systems represent the crystals with nonspherical flexible molecules / molecular fragments and with different types of intermolecular interactions, ranging from van der Waals interactions to hydrogen bonds of various types ( OH ... O, NH ... OH, NH ... O= C). A special attention is payed to the studies of solid drugs ( polymorphs of paracetamol), amino acids ( polymorphs of glycine, L- serine, D, L- serine), and dipeptides ( glycilglycine and glycilglycine hydrate) by structural, spectroscopic and calorimetric techniques. The anisotropy of structural distortion within the range of stability of the same phase, as well as the phase transitions induced by changes in temperature or pressure are discussed.
引用
收藏
页码：128 / 155
页数：28
相关论文
共 83 条
  • [31] A new pure paracetamol for direct compression: The orthorhombic form
    DiMartino, P
    GuyotHermann, AM
    Conflant, P
    Drache, M
    Guyot, JC
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1996, 128 (1-2) : 1 - 8
  • [32] Variable temperature (100-360 K) single-crystal X-ray diffraction study of the orthorhombic polymorph of paracetamol (p-hydroxyacetanilide)
    Drebushchak, TN
    Boldyreva, EV
    [J]. ZEITSCHRIFT FUR KRISTALLOGRAPHIE, 2004, 219 (08): : 506 - 512
  • [33] DREBUSHCHAK TN, 2004, UNPUB RUSS J STRUCT
  • [34] Synthesis and calorimetric investigation of unstable β-glycine
    Drebushchak, VA
    Boldyreva, EV
    Drebushchak, TN
    Shutova, ES
    [J]. JOURNAL OF CRYSTAL GROWTH, 2002, 241 (1-2) : 266 - 268
  • [35] DISAPPEARING POLYMORPHS
    DUNITZ, JD
    BERNSTEIN, J
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (04) : 193 - 200
  • [36] FABBIANI FPA, 2004, CRYSTENGCOMM, P1
  • [37] Polarization switching of crystal structure in the nonphotochemical light-induced nucleation of supersaturated aqueous glycine solutions
    Garetz, BA
    Matic, J
    Myerson, AS
    [J]. PHYSICAL REVIEW LETTERS, 2002, 89 (17) : 1 - 175501
  • [38] Gavezzotti A., 1998, CRYSTALLOGR REV, V7, P5, DOI DOI 10.1080/08893119808035402
  • [39] X-ray scattering from surfaces of organic crystals
    Gidalevitz, D
    Feidenhansl, R
    Smilgies, DM
    Leiserowitz, L
    [J]. SURFACE REVIEW AND LETTERS, 1997, 4 (04) : 721 - 732
  • [40] Monitoring in situ growth and dissolution of molecular crystals: Towards determination of the growth units
    Gidalevitz, D
    Feidenhansl, R
    Matlis, S
    Smilgies, DM
    Christensen, MJ
    Leiserowitz, L
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (09): : 955 - 959
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