Lercanidipine-induced chylous ascites: Case report and literature review

被引：5

作者：

Basualdo, J. E. ^{[1
]}

Rosado, I. A. ^{[1
]}

Morales, M. I. ^{[2
]}

Fernandez-Ros, N. ^{[1
]}

Huerta, A. ^{[1
]}

Alegre, F. ^{[1
]}

Landecho, M. F. ^{[1
]}

Lucena, J. F. ^{[1
]}

机构：

[1] Clin Univ Navarra, Div Intermediate Care & Hosp Unit, Dept Internal Med, Pamplona, Spain

[2] Clin Univ Navarra, Dept Nucl Med, Pamplona, Spain

来源：

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2017年 / 42卷 / 05期

关键词：

adverse drug reaction; calcium channel blockers; chylous ascites; lercanidipine; INDUCED CHYLOPERITONEUM; PATIENT;

D O I：

10.1111/jcpt.12555

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

What is known and objectiveChylous ascites is a rare condition. The most frequent causes are lymphomas, solid malignancies, abdominal trauma and cirrhosis. Isolated case reports describe the relationship between calcium channel blockers (CCB) and chyloperitoneum. Lercanidipine is a third-generation dihydropyridine with low rate of adverse events. We describe a case of lercanidipine-induced chylous ascites. Case summaryAn 80-year-old white female with hypertension treated with lercanidipine, developed chylous ascites and abdominal pain after the dosage of the CCB was doubled. The initial suspicion was a hidden neoplasm, but after a thorough research, no apparent cause was detected and the symptoms resolved after the drug was suspended. What is new and conclusionCalcium channel blockers should be considered as possible causes in cases of chyloperitoneum of unknown aetiology.

引用

页码：638 / 641

页数：4

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