Obesity and COVID-19: What are the Consequences?

被引:20
作者
Steenblock, Charlotte [1 ]
Hassanein, Mohamed [2 ]
Khan, Emran G. [3 ]
Yaman, Mohamad [4 ]
Kamel, Margrit [5 ]
Barbir, Mahmoud [6 ]
Lorke, Dietrich E. [7 ]
Everett, Dean [8 ]
Bejtullah, Saqipi [9 ]
Lohmann, Tobias [10 ]
Lindner, Uwe [11 ]
Tahirukaj, Ermal [1 ]
Jirjees, Feras Jassim [12 ]
Soliman, Sameh S. M. [12 ]
Quitter, Friederike [13 ]
Bornstein, Stefan R. [1 ,14 ]
机构
[1] Univ Klinikum Carl Gustav Carus, Dept Med 3, Dresden, Germany
[2] Dubai Hosp, Dept Diabet & Endocrinol, Dubai, U Arab Emirates
[3] Kings Coll Hosp London, Endocrinol & Diabetol, Dubai, U Arab Emirates
[4] Nesmah Technol, Bldg 6, Dubai, U Arab Emirates
[5] Tech Univ Dresden, Ctr Regenerat Therapies Dresden, Dresden, Germany
[6] Harefield Hosp, Dept Cardiol, Harefield, Middx, England
[7] Khalifa Univ, Dept Anat & Cellular Biol, Abu Dhabi, U Arab Emirates
[8] Khalifa Univ, Dept Pathol & Infect Dis, Abu Dhabi, U Arab Emirates
[9] Coll Heimerer, Res Unit, Prishtina, Kosovo
[10] Stadt Klinikum Dresden, MK5, Dresden, Germany
[11] Klinikum Chemnitz, Internal Med 2, Chemnitz, Germany
[12] Univ Sharjah, Coll Pharm, Sharjah, U Arab Emirates
[13] Univ Klinikum Carl Gustav Carus, Klin Kinder & Jugendmed, Dresden, Germany
[14] Kings Coll London, Fac Life Sci & Med, Sch Cardiovasc & Metab Med & Sci, London, England
关键词
obesity; metabolic syndrome; COVID-19; long-COVID; inflammation; ADIPOSE-TISSUE BIOLOGY; CIRCULATING ADIPONECTIN; INFLAMMATION; CORONAVIRUS; OVERWEIGHT; EXPRESSION; BINDING; ACE2; SEX;
D O I
10.1055/a-1878-9757
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity is an increasing health problem all over the world. In combination with the current COVID-19 pandemic, this has turned into a massive challenge as individuals with overweight and obesity at all ages show a significant increase in their risk of getting severe COVID-19. Around 20% of all patients that were hospitalized for COVID-19 suffered from obesity alone, whereas obesity in combination with other metabolic comorbidities, such as type 2 diabetes and hypertension, account for up to 60% of all hospitalizations in relation to COVID-19. Therefore, it is of immense importance to put the spotlight on the high incidence of obesity present already in childhood both by changing the individual minds and by encouraging politicians and the whole society to commence preventive interventions for achieving a better nutrition for all social classes all over the world. In the current review, we aim to explain the different pathways and mechanisms that are responsible for the increased risk of severe COVID-19 in people with overweight and obesity. Furthermore, we discuss how the pandemic has led to weight gains in many people during lockdown. At the end, we discuss the importance of preventing such an interface between a non-communicable disease like obesity and a communicable disease like COVID-19 in the future.
引用
收藏
页码:496 / 502
页数:7
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