Fournier's Gangrene: Series of Twenty Patients

Background and Purpose: Fournier's gangrene (FG) is a rare, rapidly progressive, fulminant form of necrotizing fasciitis of the genital, perianal and perineal regions. Our aim is to investigate the clinical signs, symptoms and factors which affect the clinical results of patients with FG in our clinic. Patients and Methods: 20 patients having FG were admitted to our department during the past 6-year period. Age, gender, diabetes mellitus (DM), duration of symptoms, FG severity index score (FGSIS), colostomy, hospitalization time and number of debridements were investigated for their effects. Results: 13 of our patients were male, 7 of them were female. The mean age was 52.2 years (range: 30-80 years). 85% of our patients had DM as a predisposing factor. The mean hospitalization time was 19.7 days (range: 6-45 days), and overall mortality was 20% (4 patients). Age and FGSIS have been found to be statistically significant factors among the parameters studied. Discussion: FG is still an important disease with high mortality rates in spite of the developments in intensive care units and new-generation antibiotics. In conclusion, we have found that the age and FGSIS of the patient are the most important effecting factors. Copyright (C) 2010 S. Karger AG, Basel