Therapeutic Strategy for Gastrointestinal Bleeding in Patients With Left Ventricular Assist Device

被引：25

作者：

Imamura, Teruhiko ^{[1
]}

Kinugawa, Koichiro ^{[2
]}

Uriel, Nir ^{[1
]}

机构：

[1] Univ Chicago, Med Ctr, Dept Med, Chicago, IL 60637 USA

[2] Toyama Univ, Dept Internal Med 2, 2630 Sugitani, Toyama 9300194, Japan

来源：

CIRCULATION JOURNAL | 2018年 / 82卷 / 12期

基金：

日本学术振兴会;

关键词：

Angiogenesis; HeartMate; Hemocompatibility; Left ventricular assist device (LVAD); Omega-3; VON-WILLEBRAND-FACTOR; HEARTMATE II; ARTERIOVENOUS-MALFORMATIONS; CIRCULATORY PUMP; LONG-TERM; SUPPORT; ANGIOGENESIS; THALIDOMIDE; OCTREOTIDE; OUTCOMES;

D O I：

10.1253/circj.CJ-18-0883

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Left ventricular assist device (LVAD) technology has improved the survival of advanced heart failure patients. However, readmission rates following LVAD implantation remain high and are an unsolved matter. Currently, gastrointestinal bleeding is one of the major causes of readmission and has recently been demonstrated to mainly result from increased angiogenesis. In addition to the conventional therapeutic strategies, including a reduction in antiplatelet and anticoagulation therapies and blood products administration, several therapeutic tools have recently been proposed: octreotide, thalidomide, hemodynamic optimization by the ramp test, and fish oil therapy. This review will update the therapeutic strategy for gastrointestinal bleeding in LVAD patients.

引用

页码：2931 / 2938

页数：8

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