PET-CT staging of the neck in cancers of the oropharynx: patterns of regional and retropharyngeal nodal metastasis

被引:19
作者
Tauzin, Marcie [1 ]
Rabalais, Amy [1 ]
Hagan, Joseph L. [2 ]
Wood, Charles G. [3 ]
Ferris, Robert L. [4 ]
Walvekar, Rohan R. [1 ]
机构
[1] LSU Hlth Sci Ctr, Dept Otolaryngol Head & Neck Surg, New Orleans, LA USA
[2] LSU Hlth Sci Ctr, Sch Publ Hlth, Biostat Program, New Orleans, LA USA
[3] Mary Bird Perkins Canc Ctr, Baton Rouge, LA USA
[4] Univ Pittsburgh, Dept Otolaryngol Head Neck Surg, Pittsburgh, PA USA
关键词
SQUAMOUS-CELL-CARCINOMA; POSITRON-EMISSION-TOMOGRAPHY; COMPUTED-TOMOGRAPHY; NORMAL ANATOMY; LYMPH-NODES; HEAD; SURGERY; HYPOPHARYNX; DISSECTION; VARIANTS;
D O I
10.1186/1477-7819-8-70
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objective: To study the retropharyngeal lymph node status (RPLN) by pretreatment PET-CT imaging in patients with squamous cell carcinomas of the oropharynx (OPSCC). Study Design: Retrospective. Methods: 101 patients with a biopsy proven OPSCC were identified. 53 patients meeting inclusion criteria were further analyzed. Results: The frequency of RPLN was 20.8% (11/53). Advanced T stage cancer (OR = 5.6250, 95% CI: 1.06 - 29.80, p = 0.0410) and advanced clinical N stage cancer (i.e. N2+) had higher odds (OR = 3.9773, 95% CI: 0.9628 - 16.4291) of being RPLN positive as compared to N0-1 patients. Conclusions: Pre-treatment PET-CT can be used as a staging tool to aid in treatment planning of OPSCC, as rates of RPLN and nodal metastasis are consistent with those reported in the literature. Advanced T and N stage are associated with a greater odds ratio of being RPLN positive by PET-CT imaging.
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页数:5
相关论文
共 23 条
[1]   Significance of retropharyngeal node dissection at radical surgery for carcinoma of the hypopharynx and cervical esophagus [J].
Amatsu, M ;
Mohri, M ;
Kinishi, M .
LARYNGOSCOPE, 2001, 111 (06) :1099-1103
[2]   SIGNIFICANCE OF RETROPHARYNGEAL NODES IN CANCER OF THE HEAD AND NECK [J].
BALLANTYNE, AJ .
AMERICAN JOURNAL OF SURGERY, 1964, 108 (04) :500-504
[3]   Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States [J].
Chaturvedi, Anil K. ;
Engels, Eric A. ;
Anderson, William F. ;
Gillison, Maura L. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (04) :612-619
[4]  
Galati LT, 2000, HEAD NECK-J SCI SPEC, V22, P294, DOI 10.1002/(SICI)1097-0347(200005)22:3<294::AID-HED13>3.0.CO
[5]  
2-9
[6]   Impact of retropharyngeal lymph node metastasis in head and neck squamous cell carcinoma [J].
Gross, ND ;
Ellingson, TW ;
Wax, MK ;
Cohen, JI ;
Andersen, PE .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2004, 130 (02) :169-173
[7]   RETROPHARYNGEAL NODE DISSECTION IN CANCER OF THE OROPHARYNX AND HYPOPHARYNX [J].
HASEGAWA, Y ;
MATSUURA, H .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 1994, 16 (02) :173-180
[8]   Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region -: I.: Technique, complications, and functional results [J].
Holsinger, FC ;
McWhorter, AJ ;
Ménard, M ;
Garcia, D ;
Laccourreye, O .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2005, 131 (07) :583-591
[9]  
Kim SY, 2007, J NUCL MED, V48, P373
[10]  
KYZAS PA, 2001, J NATL CANCER I, V100, P712