Chemotherapy and women fertility preservation

被引：2

作者：

Gauthier, Tristan ^{[1
]}

Piver, Pascal ^{[1
]}

Durand, Lise-Marie ^{[1
]}

Donadel, Lorene ^{[1
]}

Pech, Jean-Christophe ^{[2
]}

Roux, Christophe ^{[3
]}

Aubard, Yves ^{[1
]}

机构：

[1] CHU Dupuytren, Hop Mere Enfant, Serv Gynecol Obstet, F-87000 Limoges, France

[2] CHU Dupuytren, Hop Mere Enfant, Ctr PMA, F-87000 Limoges, France

[3] CHU, Ctr PMA, F-25030 Besancon, France

来源：

PRESSE MEDICALE | 2010年 / 39卷 / 7-8期

关键词：

CRYOPRESERVED OVARIAN TISSUE; ANTI-MULLERIAN HORMONE; ANTIMULLERIAN HORMONE; FEMALE-PATIENTS; TRANSPLANTATION; CANCER; PATIENT; AMENORRHEA; FOLLICLES; PREGNANCY;

D O I：

10.1016/j.lpm.2010.01.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Agressive chemotherapy can lead to premature ovarian failure and loss of fertility in women and children. Embryo cryopreservation is an established clinical procedure of fertility preservation but with several limitations. Others options are available. Cryopreservation ovarian cortex tissu have to be suggested in case of high gonadotoxic treatment. It doesn't require puberty and delay in initiation of chemotherapy. The first birth in France after orthotopic graft of ovarian tissu thawed have been recently described with a promising process. Oocyte cryopreservation is available for women without partner but the experience is limited. Gonadotrophin-releasing hormone (GnRH) agonist therapy as ovarian protectants seem interesting. Follicular growth and maturation in vitro are still experimental.

引用

页码：786 / 793

页数：8

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