Enzymatic alpha(2-3)-sialylation of non-natural disaccharides with cloned sialyl-transferase

被引：29

作者：

Baisch, G ^{[1
]}

Ohrlein, R ^{[1
]}

Streiff, M ^{[1
]}

Ernst, B ^{[1
]}

机构：

[1] CIBA GEIGY AG,CENT RES LABS,CH-4002 BASEL,SWITZERLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 07期

关键词：

D O I：

10.1016/0960-894X(96)00118-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Cloned alpha(2-3)sialyltransferase from rat liver is used to sialylate lactosamine derivatives, The enzyme accepts a broad range of N-acetyl substituants. The residues encompass small and bulky aliphatic replacements as well as charged and sulfonamide groups. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：755 / 758

页数：4

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