Lymphoepithelioma-like carcinoma of the breast:: not Epstein-Barr virus-, but human papilloma virus-positive

被引：38

作者：

Kulka, Janina ^{[1
]}

Kovalszky, Itona ^{[2
]}

Svastics, Egon ^{[3
]}

Berta, Maria ^{[4
]}

Fuele, Tibor ^{[2
]}

机构：

[1] Semmelweis Univ, Fac Med, Dept Pathol 2, H-1091 Budapest, Hungary

[2] Semmelweis Univ, Dept Pathol 1, H-1085 Budapest, Hungary

[3] Hungarian Railway Hosp, Dept Surg, H-1121 Budapest, Hungary

[4] Hungarian Railway Hosp, Dept Pathol, H-1121 Budapest, Hungary

来源：

HUMAN PATHOLOGY | 2008年 / 39卷 / 02期

关键词：

lymphoepithelioma-like carcinoma; breast; HPV;

D O I：

10.1016/j.humpath.2007.08.006

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ. (C) 2008 Elsevier Inc. All rights reserved.

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收藏

页码：298 / 301

页数：4

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