Differential near-field scanning optical microscopy using sensor arrays

被引:8
|
作者
Ozcan, Aydogan [1 ,2 ]
Cubukcu, Ertugrul [3 ]
Bilenca, Alberto [4 ]
Bouma, Brett E. [4 ,5 ]
Capasso, Federico [3 ]
Tearney, Guillermo J. [4 ,6 ]
机构
[1] Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Biomed Engn IDP, Los Angeles, CA 90095 USA
[3] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
[4] Harvard Univ, Sch Med, Boston, MA 02114 USA
[5] Harvard Univ, MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA
[6] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
关键词
differential NSOM (DNSOM); near-field imaging; near-field scanning optical microscopy (NSOM); SNOM;
D O I
10.1109/JSTQE.2007.910799
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
In this paper, we introduce a new aperture-type near-field scanning optical microscopy (NSOM) imaging concept that relies on specially designed large-area (e.g., >200 nm x 200 nm) aperture geometries having sharp corners. Unlike in conventional NSOM, the spatial resolution of this near-field imaging modality is not determined by the size of the aperture, but rather by the sharpness of the corners of the large aperture. This approach significantly improves the light throughput of the near-field probe and, hence, increases the SNR. Here, we discuss the basic concepts of this near-field microscopy approach and illustrate both theoretically and experimentally how an array of detectors can be utilized to further improve the SNR of the near-field image. The results of this work are particularly relevant for imaging of biological samples at a spatial resolution of <50 nm with significantly improved image quality.
引用
收藏
页码:1721 / 1729
页数:9
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