Membrane-anchored peptide inhibits human immunodeficiency virus entry

被引：101

作者：

Hildinger, M

Dittmar, MT

Schult-Dietrich, P

Fehse, B

Schnierle, BS

Thaler, S

Stiegler, G

Welker, R

von Laer, D ^{[1
]}

机构：

[1] Georg Speyer Haus, Paul Ehrlich Str 42-44, D-60596 Frankfurt, Germany

[2] Univ Hamburg, Heinrich Pette Inst Expt Virol & Immunol, D-20251 Hamburg, Germany

[3] Univ Hamburg, Krankenhaus Eppendorf, Zentrum Knochenmarktransplantat, D-20251 Hamburg, Germany

[4] Inst Appl Microbiol, A-1190 Vienna, Austria

来源：

JOURNAL OF VIROLOGY | 2001年 / 75卷 / 06期

关键词：

D O I：

10.1128/JVI.75.6.3038-3042.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Peptides derived from the heptad repeats of human immunodeficiency virus (HIV) gp41 envelope glycoprotein, such as T20, can efficiently inhibit HIV type 1 (HIV-1) entry. In this study, replication of HTV-1 was inhibited more than 100-fold in a T-helper cell line transduced with a retrovirus vector expressing membrane-anchored T20 on the cell surface. Inhibition was independent of coreceptor usage.

引用

页码：3038 / 3042

页数：5

共 50 条

[31] Dynamic structure of membrane-anchored Arf•GTP
Liu, Yizhou
Kahn, Richard A.
Prestegard, James H.
NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2010, 17 (07) : 876 - U128
[32] Membrane-anchored proteases in endothelial cell biology
Antalis, Toni M.
Conway, Gregory D.
Peroutka, Raymond J.
Buzza, Marguerite S.
CURRENT OPINION IN HEMATOLOGY, 2016, 23 (03) : 243 - 252
[33] Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors
Maamra, M
Bidlingmaier, M
Postel-Vinay, MC
Wu, Z
Strasburger, CJ
Ross, RJM
ENDOCRINOLOGY, 2001, 142 (10) : 4389 - 4393
[34] Replicating Vesicular Stomatitis Virus Vectors (VSV) Expressing Membrane-Anchored MPER Immunogens
Yuan, M.
Kemelman, M.
Lopez, M.
Wilson, A.
Arendt, H. H.
Martinez, J.
Domi, A.
DeStefano, J.
King, C. R.
Lindsay, R. W.
Parks, C. L.
AIDS RESEARCH AND HUMAN RETROVIRUSES, 2013, 29 (11) : A140 - A140
[35] Heterobiaryl Human Immunodeficiency Virus Entry Inhibitors
Lu, Rong-Jian
Tucker, John A.
Pickens, Jason
Ma, You-An
Zinevitch, Tatiana
Kirichenko, Olga
Konoplev, Vitalii
Kuznetsova, Svetlana
Sviridov, Sergey
Brahmachary, Enugurthi
Khasanov, Alisher
Mikel, Charles
Yang, Yang
Liu, Changhui
Wang, Jian
Freel, Stephanie
Fisher, Shelly
Sullivan, Alana
Zhou, Jiying
Stanfield-Oakley, Sherry
Baker, Brian
Sailstad, Jeff
Greenberg, Michael
Bolognesi, Dani
Bray, Brian
Koszalka, Barney
Jeffs, Peter
Jeffries, Cynthia
Chucholowski, Alexander
Sexton, Connie
JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (14) : 4481 - 4487
[36] Estimating the Stoichiometry of Human Immunodeficiency Virus Entry
Magnus, Carsten
Rusert, Peter
Bonhoeffer, Sebastian
Trkola, Alexandra
Regoes, Roland R.
JOURNAL OF VIROLOGY, 2009, 83 (03) : 1523 - 1531
[37] SOLUBLE AND MEMBRANE-ANCHORED FORMS OF THE HUMAN IFN-ALPHA/BETA RECEPTOR
NOVICK, D
COHEN, B
TAL, N
RUBINSTEIN, M
JOURNAL OF LEUKOCYTE BIOLOGY, 1995, 57 (05) : 712 - 718
[38] A human claudin-1-derived peptide inhibits hepatitis C virus entry
Si, Youhui
Liu, Shufeng
Liu, Xiuying
Jacobs, Jana L.
Cheng, Min
Niu, Yuqiang
Jin, Qi
Wang, Tianyi
Yang, Wei
HEPATOLOGY, 2012, 56 (02) : 507 - 515
[39] A proteomic approach to identification of transmembrane proteins and membrane-anchored proteins of Arabidopsis thaliana by peptide Sequencing
Sazuka, T
Keta, S
Shiratake, K
Yamaki, S
Shibata, D
DNA RESEARCH, 2004, 11 (02) : 101 - 113
[40] Enhanced Exposure of the CD4-Binding Site to Neutralizing Antibodies by Structural Design of a Membrane-Anchored Human Immunodeficiency Virus Type 1 gp120 Domain
Wu, Lan
Zhou, Tongqing
Yang, Zhi-yong
Svehla, Krisha
O'Dell, Sijy
Louder, Mark K.
Xu, Ling
Mascola, John R.
Burton, Dennis R.
Hoxie, James A.
Doms, Robert W.
Kwong, Peter D.
Nabel, Gary J.
JOURNAL OF VIROLOGY, 2009, 83 (10) : 5077 - 5086

← 1 2 3 4 5 →