Early experiences with tachycardia-triggered vagus nerve stimulation using the AspireSR stimulator

被引：16

作者：

El Tahry, Riem ^{[1
]}

Hirsch, Martin ^{[2
]}

Van Rijckevorsel, Kenou ^{[1
]}

Santos, Susana Ferrao ^{[1
]}

de Tourtchaninoff, Marianne ^{[1
]}

Rooijakkers, Herbert ^{[3
]}

Coenen, Volker ^{[4
]}

Schulze-Bonhage, Andreas ^{[2
]}

机构：

[1] Catholic Univ Louvain, Clin Univ St Luc, Dept Neurol, Ctr Refractory Epilepsy, Ave Hippocrate 10, B-1200 Brussels, Belgium

[2] Univ Freiburg, Med Ctr, Epilepsy Ctr, Fac Medecine, Freiburg, Germany

[3] Catholic Univ Louvain, Clin Univ St Luc, Dept Neurosurg, B-1200 Brussels, Belgium

[4] Univ Freiburg, Med Ctr, Dept Stereotact & Funct Neurosurg, Fac Medecine, Freiburg, Germany

来源：

EPILEPTIC DISORDERS | 2016年 / 18卷 / 02期

关键词：

refractory epilepsy; vagus nerve stimulation; ictal tachycardia; closed-loop stimulation; REFRACTORY EPILEPSY; ICTAL TACHYCARDIA; HEART-RATE; LONG-TERM; SEIZURES; CHILDREN; PATIENT;

D O I：

10.1684/epd.2016.0831

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Many epilepsy patients treated with vagus nerve stimulation additionally use an "on-demand" function, triggering an extra stimulation to terminate a seizure or diminish its severity. Nevertheless, a substantial number of patients are not able to actively trigger stimulations by use of a magnet, due to the absence of an aura or inability for voluntary actions in the early phase of a seizure. To address this need, a novel implantable pulse generator, the AspireSR VNS system, was developed to provide automated ictal stimulation triggered by a seizure-detecting algorithm. We report our experience with three patients in assessing the functionality of ictal stimulation, illustrating the detection system in practice. Detection of ictal tachycardia and variable additional detections of physiological tachycardia depended on the individual seizure-detecting algorithm settings.

引用

页码：155 / 162

页数：8

共 21 条

[11] Long-term results of vagus nerve stimulation in children and adolescents with drug-resistant epilepsy [J].