Highly diastereoselective synthesis of β-amino alcohols

被引：7

作者：

Meester, WJN

van Dijk, R

van Maarseveen, JH

Rutjes, FPJT

Hermkens, PHH

Hiemstra, H

机构：

[1] Univ Amsterdam, Inst Mol Chem, NL-1018 WS Amsterdam, Netherlands

[2] Univ Nijmegen, Dept Organ Chem, NL-6525 ED Nijmegen, Netherlands

[3] NV Organon, Lead Discovery Unit, NL-5340 BH Oss, Netherlands

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 22期

关键词：

D O I：

10.1039/b108254j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several substituted beta -amino alcohols 1 were synthesised in a diastereoselective manner via the novel highly versatile intermediate 8b, involving a combination of N-acyliminium ion and Weinreb amide chemistry.

引用

页码：2909 / 2911

页数：3

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