Stereoselective synthesis of 2,3-disubstituted dihydrobenzofuran using alkyne Prins type cyclization to vinylogous carbonates

被引：0

作者：

Gharpure, Santosh J. ^{[1
]}

Prasath, V. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India

来源：

JOURNAL OF CHEMICAL SCIENCES | 2011年 / 123卷 / 06期

关键词：

Vinylogous carbonates; Prins cyclization; Lewis acids; Sonogashira coupling; RADICAL CYCLIZATION; STYRENYL SYSTEMS; ACID; EFFICIENT; CONSTRUCTION; PRODUCTS; LIGNANS; 2-ARYL-2,3-DIHYDROBENZOFURANS; TETRAHYDROFURANS; REGIOSELECTIVITY;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An intramolecular, alkyne Prins type cyclization of vinylogous carbonates derived from o-alkynyl phenols is developed for the stereoselective construction of trans-2,3-disubstituted dihydrobenzofuran derivatives. Strong Lewis acids like TMSOTf catalyse this reaction efficiently. The presence of mildly electron donating groups on aryl rings increases the efficiency of the reaction.

引用

页码：943 / 949

页数：7

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