Non-movement disorder heralds symptoms of Machado-Joseph disease years before ataxia

被引：18

作者：

D'Abreu, A

Friedman, J

Coskun, J

机构：

[1] Brown Univ, Mem Hosp Rhode Isl, Dept Neurol, Pawtucket, RI 02860 USA

[2] Brown Univ, Sch Med, Dept Clin Neurosci, Providence, RI 02912 USA

来源：

MOVEMENT DISORDERS | 2005年 / 20卷 / 06期

关键词：

Machado-Joseph disease; peripheral neuropathy; cramps; non-motor manifestations; REM sleep behavior disorder;

D O I：

10.1002/mds.20419

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe three patients with the Machado-Joseph disease (MJD) genetic abnormality who had nonmovement disorder neurological symptoms or signs that preceded the gait ataxia by several years. This implies that some clinical manifestations other than ataxia may be considered part of the herald symptoms of MJD, especially in the setting of a positive family history. (c) 2005 Movement Disorder Society.

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收藏

页码：739 / 741

页数：3

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