(S)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione

被引：3

作者：

Cheng, Mao-Sheng ^{[1
]}

Ma, Chao ^{[1
]}

Liu, Jing-Hong ^{[1
]}

Sha, Yu ^{[1
]}

Wang, Qing-He ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2007年 / 63卷

关键词：

D O I：

10.1107/S1600536807054979

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title chiral compound, C12H12N2O2, was prepared by an intramolecular cyclization reaction of (S)-methyl 1-(2-nitrobenzyl)-5-oxopyrrolidine-2-carboxylate in the presence of EtOH/Fe. In the molecule, the seven-membered ring adopts a twist-boat conformation, while the five-membered ring shows a typical envelope conformation. The crystal structure is stabilized by intermolecular N-H center dot center dot center dot O hydrogen bonding.

引用

页码：O4605 / U4107

页数：9

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