Epilepsy in the elderly

被引：24

作者：

Johnston, Ann ^{[1
,2
]}

Smith, Phil E. M. ^{[2
,3
]}

机构：

[1] Morriston Hosp, Dept Neurol, Swansea, W Glam, Wales

[2] Swansea Univ, Sch Med, Inst Life Sci, Wales Epilepsy Res Network, Swansea SA2 8PP, W Glam, Wales

[3] Univ Wales Hosp, Epilepsy Unit, Cardiff CF4 4XW, S Glam, Wales

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2010年 / 10卷 / 12期

关键词：

comorbidities; diagnosis; drug interactions; elderly; epilepsy; polypharmacy; RANDOMIZED CONTROLLED-TRIAL; NEWLY-DIAGNOSED EPILEPSY; ANTIEPILEPTIC DRUG-USE; UNPROVOKED SEIZURES; LAMOTRIGINE THERAPY; GERIATRIC EPILEPSY; OLDER VETERANS; DOUBLE-BLIND; CARBAMAZEPINE; POPULATION;

D O I：

10.1586/ERN.10.170

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Epilepsy is the most common serious neurological disorder in the elderly after stroke and dementia. It may be more important for elderly people because it is intermittent and unpredictable. There is no reliable diagnostic test and so its diagnosis and management requires clinical acumen and experience. The situation is further complicated because the elderly may have many comorbidities and therefore may have many other reasons for losing consciousness. Despite their growing number, there is remarkably little research to underpin the best epilepsy management in the elderly. This article summarizes the scope of epilepsy in elderly people, highlights cerebrovascular and neurodegenerative diseases as the main underlying etiologies, explores the diagnostic challenges in this age group, including the hurdles and processes in their investigation, and examines pertinent clinical management issues.

引用

页码：1899 / 1910

页数：12

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