Chromium propionate in broilers: effect on insulin sensitivity

被引:34
作者
Brooks, M. A. [1 ,4 ]
Grimes, J. L. [2 ]
Lloyd, K. E. [1 ]
Krafka, K. [3 ]
Lamptey, A. [3 ]
Spears, J. W. [1 ]
机构
[1] N Carolina State Univ, Dept Anim Sci, Box 7621, Raleigh, NC 27695 USA
[2] N Carolina State Univ, Prestage Dept Poultry Sci, Raleigh, NC 27695 USA
[3] Kemin Agrifoods North Amer Inc, Des Moines, IA 50301 USA
[4] Oregon Zoo, Portland, OR 97077 USA
关键词
chromium; insulin; broiler; glucose; IN-VIVO; GROWTH-PERFORMANCE; DIETARY CHROMIUM; TRIVALENT CHROMIUM; NICOTINIC-ACID; GLUCOSE-UPTAKE; SERUM TRAITS; HEAT-STRESS; FATTY-ACID; METABOLISM;
D O I
10.3382/ps/pew018
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
The objective of this study was to evaluate the effects of dietary chromium (Cr), as chromium propionate, on measures of insulin sensitivity. Liver and muscle glycogen, and plasma glucose and non-esterified fatty acid (NEFA) concentrations were used as indicators of insulin sensitivity. In total, 288 newly hatched male Ross broilers were divided into 4 dietary treatments consisting of 0 (control diet analyzed 0.43 to 0.45 mg Cr/kg), 0.2, 0.4, or 0.6 mg supplemental Cr/kg diet, resulting in 4 treatments with 9 replicate pens per treatment containing eight birds per pen. At d 21, 2 birds per cage were removed based on the greatest deviation from pen mean BW, resulting in each pen containing 6 birds for the final analyses. Final BW were taken on d 40, and on d 42 two birds from each pen were sampled for plasma NEFA, glucose, and muscle and liver glycogen determination at the initiation and termination of a 22 h fast. The remaining 2 fasted birds were sampled after a 30 min refeeding period. No differences were observed in feed intake, BW gain, or feed efficiency on d 21 or d 40. Liver glycogen tended (P = 0.10) to be greater in Cr-supplemented chicks in the fed state, and muscle glycogen concentrations tended (P = 0.07) to be greater in Cr-supplemented chicks compared with controls following fasting and refeeding. Plasma glucose concentrations were not affected by dietary Cr in the fed, fasted, or refed state. Plasma NEFA levels were not affected by treatment in fed or fasted birds. However, plasma NEFA concentrations were lower (P < 0.01) in chicks supplemented with Cr than in controls following fasting and refeeding, suggesting that Cr increased insulin sensitivity. No differences were detected among birds supplemented with 0.2 or 0.4 mg Cr/kg, and among those receiving 0.4 or 0.6 mg Cr/kg. Results of this study indicate that Cr propionate supplementation of a control diet containing 0.43 to 0.45 mg Cr/kg enhanced insulin sensitivity.
引用
收藏
页码:1096 / 1104
页数:9
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