Surface and Antimicrobial Properties of N-Palmitoyl Amino Acid-Based Surfactants

被引：18

作者：

Sreenu, Madhumanchi ^{[1
]}

Nayak, Rati Ranjan ^{[1
]}

Prasad, Rachapudi Badari Narayana ^{[1
]}

Poornachandra, Yedla ^{[2
]}

Kumar, C. Ganesh ^{[2
]}

机构：

[1] CSIR Indian Inst Chem Technol, Ctr Lipid Res, Hyderabad 500007, Andhra Pradesh, India

[2] CSIR Indian Inst Chem Technol, Med Chem & Pharmacol Div, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY | 2015年 / 36卷 / 06期

关键词：

Amino acids; antimicrobial properties; emulsion stability; palmitic acid; surface active properties; BIOLOGICAL-PROPERTIES; ANTIBIOTICS;

D O I：

10.1080/01932691.2014.921626

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Synthesized sodium N-pamitoyl amino acids were evaluated for surface and antimicrobial properties and compared with sodium lauryl sulfate (SLS). Emulsion stability of the amino acid surfactants and calcium tolerance of the sodium N-palmitoyl isoleucine were better as compared to SLS. Wetting ability and foaming properties of the palmitic acid-based surfactants were inferior to SLS. N-Acyl amino acids exhibited better antibacterial activity compared to sodium salts of N-acyl amino acids and standard compounds against Staphylococcus aureus MLS-16 and Bacillus subtilis. These studies revealed that the palmitoyl amino acid surfactants can be exploited in household, skin care formulations, and industrial applications.

引用

页码：765 / 771

页数：7

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