Zinc-Catalyzed Chemoselective Reduction of Esters to Alcohols

被引：67

作者：

Das, Shoubhik ^{[1
]}

Moeller, Konstanze ^{[1
]}

Junge, Kathrin ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse EV, D-18059 Rostock, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2011年 / 17卷 / 27期

关键词：

alcohols; catalysis; chemoselectivity; reduction; zinc; DICARBOXYLIC-ACID ESTERS; METAL HYDRIDE CATALYSTS; SELECTIVE HYDROGENATION; RUTHENIUM COMPLEXES; CARBONYL-COMPOUNDS; CHIRAL ALCOHOLS; KETONES; ALDEHYDES; EFFICIENT; SYSTEM;

D O I：

10.1002/chem.201100800

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Economical alcohols! A general and chemoselective catalytic reduction of esters to alcohols using inexpensive zinc acetate and silanes has been developed. The operational simplicity and the high functional group tolerance, without the need for protecting and deprotecting steps, make this procedure particularly attractive for organic synthesis. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：7414 / 7417

页数：4

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