Synthesis and antiviral evaluation of some carbonucleoside analogues

被引：5
|
作者：
Alho, MAM
Errea, MI
Sguerra, VL
D'Accorso, NB [1 ]
Talarico, LB
García, CC
Damonte, EB
机构：
[1] Consejo Nacl Invest Cient & Tecn, CIHIDECAR, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1033 Buenos Aires, DF, Argentina
[2] Fac Ciencias Exactas & Nat Buenos Aires, Dept Quim Biol, Buenos Aires, DF, Argentina
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 42卷 / 05期
关键词：
D O I：
10.1002/jhet.5570420536
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1,2-O-Isopropylidene-alpha-L-threofuranosyl heterocyclic derivatives were synthesized from 1,2-O-isopropylidene-alpha-D-xilopentadialdo-1,4-furanose and tested for antiviral activity against herpes simplex virus type 1, dengue virus type 2 and Junin virus. For comparative propose, the antiviral activity of some of their pyranosyl analogues were also tested. The furanosyl derivatives showed to be moderate inhibitors of Junin virus and, in general, proved to be more effective than the pyranosyl analogues.
引用
收藏
页码：979 / 983
页数：5
相关论文
共 50 条
  • [21] Synthesis of Novel 6-Azapyrimidine Acyclic Nucleoside Analogues and Antiviral Evaluation
    Jasamai, Malina
    Simons, Claire
    Balzarini, Jan
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2010, 29 (07): : 535 - 541
  • [22] Synthesis and Antiviral Evaluation of (-)-3′-Methylcarbovir, (-)-3′-Methylabacavir, and Modified Purine Analogues
    Bremond, Paul
    Audran, Gerard
    Monti, Honore
    De Clercq, Erik
    Pannecouque, Christophe
    SYNTHESIS-STUTTGART, 2009, (02): : 290 - 296
  • [23] Synthesis and antiviral evaluation of novel N-6 substituted adenosine analogues
    Hao, Youwu
    Zhou, Gaohui
    Wu, Wei
    Zhang, Yang
    Tao, Liming
    Yao, Jianhua
    Xu, Wenping
    TETRAHEDRON LETTERS, 2017, 58 (03) : 190 - 193
  • [24] Synthesis and antiviral and antineoplastic activities of some novel carbocyclic guanosine analogues with a cyclobutane ring
    Blanco, JM
    Caamaño, O
    Fernández, F
    García-Mera, X
    Hergueta, AR
    López, C
    Rodríguez-Borges, JE
    Balzarini, J
    De Clercq, E
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1999, 47 (09) : 1314 - 1317
  • [25] Synthesis and antiviral evaluation of some sugar arylglycinoylhydrazones and their oxadiazoline derivatives
    Abdel-Aal, Mohammed T.
    El-Sayed, Wael A.
    El-Ashry, El-Sayed H.
    ARCHIV DER PHARMAZIE, 2006, 339 (12) : 656 - 663
  • [26] Synthesis and biological evaluation of some stilbene-based analogues
    Karki, Subhas S.
    Bhutle, Santosh R.
    Pedgaonkar, Ganesh S.
    Zubaidha, P. K.
    Shaikh, Rizwan M.
    Rajput, Chitra G.
    Shendarkar, Girish S.
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (08) : 1158 - 1163
  • [27] Synthesis and Evaluation of Some New Isoquine Analogues for Antimalarial Activity
    Saha, Chandra Nath
    Bhattacharya, Sanjib
    Chetia, Dipak
    E-JOURNAL OF CHEMISTRY, 2009, 6 : S381 - S389
  • [28] Synthesis and cytotoxic evaluation of some cribrostatin-ecteinascidin analogues
    Wright, Benjamin J. D.
    Chan, Collin
    Danishefsky, Samuel J.
    JOURNAL OF NATURAL PRODUCTS, 2008, 71 (03): : 409 - 414
  • [29] Synthesis and biological evaluation of some stilbene-based analogues
    Subhas S. Karki
    Santosh R. Bhutle
    Ganesh S. Pedgaonkar
    P. K. Zubaidha
    Rizwan M. Shaikh
    Chitra G. Rajput
    Girish S. Shendarkar
    Medicinal Chemistry Research, 2011, 20 : 1158 - 1163
  • [30] Acyclic analogues of pyrazofurin: Syntheses and antiviral evaluation
    Comber, R.N.
    Gray, R.J.
    Secrist III, J.A.
    Carbohydrate Research, 1991, 216 : 441 - 452
12345