Volumetric Muscle Loss

被引:312
作者
Grogan, Brian F. [1 ]
Hsu, Joseph R. [2 ]
机构
[1] Brooke Army Med Ctr, San Antonio Uniformed Serv Hlth Educ Consortium, Dept Orthopaed & Rehabil, Ft Sam Houston, TX 78234 USA
[2] Brooke Army Med Ctr, USA, Inst Surg Res, San Antonio Uniformed Serv Hlth Educ Consortium, Ft Sam Houston, TX 78234 USA
关键词
OPERATION ENDURING FREEDOM; IRAQI FREEDOM; STEM-CELLS; RELIABILITY;
D O I
10.5435/00124635-201102001-00007
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Prevention of infection, as well as bone covering and healing, is paramount in the management of limb injury with associated muscle injury. Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle with resultant functional impairment. No standardized evaluation protocol exists for the characterization and quantification of VML. Clinical photographs and video recordings, range of motion measurements, manual muscle strength testing, and isokinetic muscle function testing may prove to be useful in documenting VML. Current treatment options include functional free muscle transfer and the use of advanced bracing designs. Advances in powered bracing and regenerative medicine may one day provide additional therapeutic options. Further research on VML is warranted.
引用
收藏
页码:S35 / S37
页数:3
相关论文
共 20 条
[1]   Chemoattraction of Progenitor Cells by Remodeling Extracellular Matrix Scaffolds [J].
Beattie, Allison J. ;
Gilbert, Thomas W. ;
Guyot, Juan Pablo ;
Yates, Adolph J. ;
Badylak, Stephen F. .
TISSUE ENGINEERING PART A, 2009, 15 (05) :1119-1125
[2]  
*BRIT MRC, 1943, AIDS INV PER NERV IN
[3]   Reliability of videotaped observational gait analysis in patients with orthopedic impairments [J].
Brunnekreef, JJ ;
van Uden, CJT ;
van Moorsel, S ;
Kooloos, JGM .
BMC MUSCULOSKELETAL DISORDERS, 2005, 6 (1)
[4]  
BURNS TC, J ORTHOP TR IN PRESS
[5]   Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles [J].
Cerletti, Massimiliano ;
Jurga, Sara ;
Witczak, Carol A. ;
Hirshman, Michael F. ;
Shadrach, Jennifer L. ;
Goodyear, Laurie J. ;
Wagers, Amy J. .
CELL, 2008, 134 (01) :37-47
[6]   Battlefield Orthopaedic Injuries Cause the Majority of Long-term Disabilities [J].
Cross, Jessica D. ;
Ficke, James R. ;
Hsu, Joseph R. ;
Masini, Brendan D. ;
Wenke, Joseph C. .
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2011, 19 :S1-S7
[7]   Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane [J].
De Bari, C ;
Dell'Accio, F ;
Vandenabeele, F ;
Vermeesch, JR ;
Raymackcrs, JM ;
Luyten, FP .
JOURNAL OF CELL BIOLOGY, 2003, 160 (06) :909-918
[8]  
Doi K, 2002, CLIN PLAST SURG, V29, P483
[9]   Reliability and validity of the Biodex system 3 pro isokinetic dynamometer velocity, torque and position measurements [J].
Drouin, JM ;
Valovich-mcLeod, TC ;
Shultz, SJ ;
Gansneder, BM ;
Perrin, DH .
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2004, 91 (01) :22-29
[10]  
FEIRING D C, 1990, Journal of Orthopaedic and Sports Physical Therapy, V11, P298