PERITONEAL PROTEIN CLEARANCE RATHER THAN FASTER TRANSPORT STATUS DETERMINES OUTCOMES IN PERITONEAL DIALYSIS PATIENTS

被引：41
|
作者：
Rajakaruna, Gayathri [1 ]
Caplin, Ben [1 ]
Davenport, Andrew [1 ]
机构：
[1] UCL, Sch Med, Royal Free Hosp, UCL Ctr Nephrol, London NW3 2PF, England
来源：
PERITONEAL DIALYSIS INTERNATIONAL | 2015年 / 35卷 / 02期
关键词：
Bioimpedance; survival; extracellular fluid; peritoneal protein loss; fast transporter; EQUILIBRATION TEST; NATRIURETIC PEPTIDE; MEMBRANE-TRANSPORT; BIOIMPEDANCE; SURVIVAL; VOLUMES;
D O I：
10.3747/pdi.2013.00217
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Faster peritoneal transport has been associated with an increased risk of therapy failure and patient mortality. However, faster transport can the result of many factors. Peritoneal protein clearance (PPC) has been proposed to distinguish faster peritoneal transport attributable to inflammatory conditions, as protein clearance reflects large-pore flow, which increases during inflammation. We followed a cohort of 300 peritoneal dialysis patients, and after adjustments for age and comorbidity, higher PPC was associated with increased risk of death (hazard ratio: 1.81; 95% confidence interval: 1.11 to 2.95), even after patients underwent transplantation or transferred to hemodialysis.
引用
收藏
页码：216 / 221
页数：6
相关论文
共 50 条
  • [21] Prognosis of Peritoneal Dialysis Patients with Different Peritoneal Transport Characteristics: A Retrospective Cohort Study
    Xia, Yangyang
    Jiang, Chunming
    Liu, Ying
    Zhang, Qingyan
    Feng, Yuan
    Zhang, Miao
    IRANIAN JOURNAL OF KIDNEY DISEASES, 2024, 18 (01) : 56 - 64
  • [22] Impact of Diabetes on Extracellular Volume Status in Patients Initiating Peritoneal Dialysis
    Udo, Aniema
    Goodlad, Catriona
    Davenport, Andrew
    AMERICAN JOURNAL OF NEPHROLOGY, 2017, 46 (01) : 18 - 25
  • [23] Peritoneal Water Transport Characteristics of Diabetic Patients Undergoing Peritoneal Dialysis: A Longitudinal Study
    Fernandes, Ana
    Ribera-Sanchez, Roi
    Rodriguez-Carmona, Ana
    Lopez-Iglesias, Antia
    Leite-Costa, Natacha
    Perez Fontan, Miguel
    AMERICAN JOURNAL OF NEPHROLOGY, 2017, 46 (01) : 47 - 54
  • [24] Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients
    Yu, Zanzhe
    Lambie, Mark
    Chess, James
    Williams, Andrew
    Do, Jun-Young
    Topley, Nicholas
    Davies, Simon J.
    FRONTIERS IN PHYSIOLOGY, 2019, 10
  • [25] THE INFLUENCE OF GLUCOSE EXPOSURE LOAD AND PERITONEAL MEMBRANE TRANSPORT ON BODY COMPOSITION AND NUTRITIONAL STATUS CHANGES AFTER 1 YEAR ON PERITONEAL DIALYSIS
    Caron-Lienert, Rafaela Siviero
    Poli-de-Figueiredo, Carlos Eduardo
    Prado Lima Figueiredo, Ana Elizabeth
    Pinheiro da Costa, Bartira Ercilia
    Crepaldi, Carlo
    Pizzato, Alessandra Campani
    Ferrari, Fiorenza
    Giuliani, Anna
    Ronco, Claudio
    PERITONEAL DIALYSIS INTERNATIONAL, 2017, 37 (04): : 458 - 463
  • [26] Relationship between dialysate oxidized protein and peritoneal membrane transport properties in patients on peritoneal dialysis
    Latcha, Sheron
    Hong, Susana
    Gibbons, Nora
    Kohn, Nina
    Mattana, Joseph
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2008, 23 (10) : 3295 - 3301
  • [27] Effects of prophylactic antibiotics before peritoneal dialysis catheter implantation on the clinical outcomes of peritoneal dialysis patients
    Liu, Xihui
    Zuo, Xiaoyan
    Sun, Xia
    Hu, Zhao
    RENAL FAILURE, 2019, 41 (01) : 16 - 23
  • [28] Recent analysis of status and outcomes of peritoneal dialysis in the Tokai area of Japan: the second report of the Tokai peritoneal dialysis registry
    Mizuno, Masashi
    Ito, Yasuhiko
    Suzuki, Yasuhiro
    Sakata, Fumiko
    Saka, Yosuke
    Hiramatsu, Takeyuki
    Tamai, Hirofumi
    Mizutani, Makoto
    Naruse, Tomohiko
    Ohashi, Norimi
    Kasuga, Hirotake
    Shimizu, Hideaki
    Kurata, Hisashi
    Kurata, Kei
    Suzuki, Satoshi
    Kido, Satoko
    Tsuruta, Yoshikazu
    Matsuoka, Teppei
    Horie, Masanobu
    Maruyama, Shoichi
    Matsuo, Seiichi
    CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2016, 20 (06) : 960 - 971
  • [29] Peritoneal fast transport in incident peritoneal dialysis patients is not consistently associated with systemic inflammation
    Rodrigues, AS
    Almeida, M
    Fonseca, I
    Martins, M
    Carvalho, MJ
    Silva, F
    Correia, C
    Santos, MJ
    Cabrita, A
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2006, 21 (03) : 763 - 769
  • [30] PERITONEAL PROTEIN LOSS, LEAKAGE OR CLEARANCE IN PERITONEAL DIALYSIS, WHERE DO WE STAND?
    Guedes, Anabela Malho
    PERITONEAL DIALYSIS INTERNATIONAL, 2019, 39 (03): : 201 - 209
12345