Serum Protein Electrophoresis and Immunofixation Electrophoresis Detection in Multiple Myeloma

被引：8
|
作者：
Zhu, Shanshan [1 ]
Li, Wei [1 ]
Lin, Meilin [1 ]
Li, Tiemin [1 ]
机构：
[1] Hebei Univ, Affiliated Hosp, Dept Clin Lab, Baoding 071000, Peoples R China
来源：
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN | 2021年 / 31卷 / 07期
关键词：
Multiple myeloma (MM); Serum protein electrophoresis; Immunofixation electrophoresis; Monoclonal immunoglobulin;
D O I：
10.29271/jcpsp.2021.07.864
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The objective of this study was to investigate the diagnostic significance of serum protein electrophoresis and immunofixation electrophoresis detection in diagnosis of multiple myeloma (MM). One hundred and five patients were investigated. The detection rate of M protein by immunofixation electrophoresis detection was better (105 cases, 100%) than that of serum protein electrophoresis (101 cases, 96.19%, p<0.001). The M band was not detected by serum protein electrophoresis in four cases (3.81%), among which one case (0.95%) was identified as IgA type and 3 cases (2.86%) as light chain type after immunoglobulin analysis. Immunofixation electrophoresis detection technique can be used for screening M protein in patients with atypical MM; and immunofixation electrophoresis detection technique can increase the diagnosis accuracy in patients with atypical MM.
引用
收藏
页码：864 / 867
页数：4
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