A fourth dose of the mRNA-1273 SARS-CoV-2 vaccine improves serum neutralization against the Delta variant in kidney transplant recipients

被引:41
作者
Benotmane, Ilies [1 ]
Bruel, Timothee [2 ,3 ]
Planas, Delphine [2 ,3 ]
Fafi-Kremer, Samira [4 ]
Schwartz, Olivier [2 ,3 ]
Caillard, Sophie [1 ]
机构
[1] Strasbourg Univ Hosp, Dept Nephrol & Transplantat, 1 Pl hop, F-67091 Strasbourg, France
[2] Univ Paris, Ctr Natl Rech scientif CNRS, Virus & Immun Unit, Unite mixte Rech UMR 3569,Inst Pasteur, Paris, France
[3] Vaccine Res Inst, Basic Div, Creteil, France
[4] Strasbourg Univ Hosp, Dept Virol, Strasbourg, France
关键词
Delta variant; fourth dose; kidney transplantation; mRNA vaccine; neutralizing antibodies; SARS-CoV-2;
D O I
10.1016/j.kint.2022.02.011
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1073 / 1076
页数:4
相关论文
共 9 条
  • [1] Antibody Response to a Fourth Dose of a SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series
    Alejo, Jennifer L.
    Mitchell, Jonathan
    Chiang, Teresa P. -Y.
    Abedon, Aura T.
    Boyarsky, Brian J.
    Avery, Robin K.
    Tobian, Aaron A. R.
    Levan, Macey L.
    Massie, Allan B.
    Garonzik-Wang, Jacqueline M.
    Segev, Dorry L.
    Werbel, William A.
    [J]. TRANSPLANTATION, 2021, 105 (12) : E280 - E281
  • [2] Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses
    Benotmane, Ilies
    Gautier, Gabriela
    Perrin, Peggy
    Olagne, Jerome
    Cognard, Noelle
    Fafi-Kremer, Samira
    Caillard, Sophie
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 326 (11): : 1063 - 1065
  • [3] Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant
    Bernal, Jamie Lopez
    Andrews, Nick
    Gower, Charlotte
    Gallagher, Eileen
    Simmons, Ruth
    Thelwall, Simon
    Stowe, Julia
    Tessier, Elise
    Groves, Natalie
    Dabrera, Gavin
    Myers, Richard
    Campbell, Colin N. J.
    Amirthalingam, Gayatri
    Edmunds, Matt
    Zambon, Maria
    Brown, Kevin E.
    Hopkins, Susan
    Chand, Meera
    Ramsay, Mary
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (07) : 585 - 594
  • [4] Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients
    Hall, Victoria G.
    Ferreira, Victor H.
    Ku, Terrance
    Ierullo, Matthew
    Majchrzak-Kita, Beata
    Chaparro, Cecilia
    Selzner, Nazia
    Schiff, Jeffrey
    McDonald, Michael
    Tomlinson, George
    Kulasingam, Vathany
    Kumar, Deepali
    Humar, Atul
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (13) : 1244 - 1246
  • [5] Assessment of 4 Doses of SARS-CoV-2 Messenger RNA-Based Vaccine in Recipients of a Solid Organ Transplant
    Kamar, Nassim
    Abravanel, Florence
    Marion, Olivier
    Romieu-Mourez, Raphaelle
    Couat, Chloe
    Del Bello, Arnaud
    Izopet, Jacques
    [J]. JAMA NETWORK OPEN, 2021, 4 (11)
  • [6] Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection
    Khoury, David S.
    Cromer, Deborah
    Reynaldi, Arnold
    Schlub, Timothy E.
    Wheatley, Adam K.
    Juno, Jennifer A.
    Subbarao, Kanta
    Kent, Stephen J.
    Triccas, James A.
    Davenport, Miles P.
    [J]. NATURE MEDICINE, 2021, 27 (07) : 1205 - +
  • [7] A third injection of the BNT162b2 mRNA COVID-19 vaccine in kidney transplant recipients improves the humoral immune response
    Masset, Christophe
    Kerleau, Clarisse
    Garandeau, Claire
    Ville, Simon
    Cantarovich, Diego
    Hourmant, Maryvonne
    Kervella, Delphine
    Houzet, Aurelie
    Guillot-Gueguen, Cecile
    Guihard, Irene
    Giral, Magali
    Dantal, Jacques
    Blancho, Gilles
    [J]. KIDNEY INTERNATIONAL, 2021, 100 (05) : 1132 - 1135
  • [8] Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization
    Planas, Delphine
    Veyer, David
    Baidaliuk, Artem
    Staropoli, Isabelle
    Guivel-Benhassine, Florence
    Rajah, Maaran Michael
    Planchais, Cyril
    Porrot, Francoise
    Robillard, Nicolas
    Puech, Julien
    Prot, Matthieu
    Gallais, Floriane
    Gantner, Pierre
    Velay, Aurelie
    Le Guen, Julien
    Kassis-Chikhani, Najiby
    Edriss, Dhiaeddine
    Belec, Laurent
    Seve, Aymeric
    Courtellemont, Laura
    Pere, Helene
    Hocqueloux, Laurent
    Fafi-Kremer, Samira
    Prazuck, Thierry
    Mouquet, Hugo
    Bruel, Timothee
    Simon-Loriere, Etienne
    Rey, Felix A.
    Schwartz, Olivier
    [J]. NATURE, 2021, 596 (7871) : 276 - +
  • [9] Subbaraman N, DO VACCINATED PEOPLE