Directing lipid transport at membrane contact sites

被引：4
|
作者：
Krauss, Michael [1 ]
Haucke, Volker [1 ,2 ]
机构：
[1] Leibniz Inst Mol Pharmakol FMP, Robert Rossle Str 10, D-13125 Berlin, Germany
[2] Free Univ Berlin, Fac Biol, Chem, Pharm, D-14195 Berlin, Germany
来源：
NATURE CELL BIOLOGY | 2016年 / 18卷 / 05期
关键词：
ER; PROTEINS;
D O I：
10.1038/ncb3345
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Contact sites between the endoplasmic reticulum and the plasma membrane mediate receptor signalling. How this function is controlled physically and functionally is poorly understood. Extended synaptotagmins are now shown to shuttle the lipid metabolite diacylglycerol from the plasma membrane to the endoplasmic reticulum in receptor-stimulated cells.
引用
收藏
页码：461 / 463
页数：4
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