IBD Exposure to anti-TNF agents in utero: controlling health risks

被引:4
作者
van der Woude, C. Janneke [1 ]
Kanis, Shannon L. [1 ]
机构
[1] Erasmus Univ, Med Ctr, Dept Gastroenterol & Hepatol, Room HS 306,S Gravendijkwal 230, NL-3015 CE Rotterdam, Netherlands
关键词
PREGNANCY;
D O I
10.1038/nrgastro.2016.94
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
A recent study reports on drug clearance in newborn babies after in utero exposure to anti-TNF antibodies, infliximab and adalimumab. As women with IBD are increasingly exposed to these drugs due to changing treatment paradigms and earlier diagnosis, this commentary explores these clinically important results.
引用
收藏
页码:387 / +
页数:2
相关论文
共 10 条
  • [1] [Anonymous], GASTROENTEROLOGY
  • [2] Detection of infliximab in breast milk of nursing mothers with inflammatory bowel disease
    Ben-Horin, Shomron
    Yavzori, Miri
    Kopylov, Uri
    Picard, Orit
    Fudim, Ella
    Eliakim, Rami
    Chowers, Yehuda
    Lang, Alon
    [J]. JOURNAL OF CROHNS & COLITIS, 2011, 5 (06) : 555 - 558
  • [3] Adalimumab Level in Breast Milk of a Nursing Mother
    Ben-Horin, Shomron
    Yavzori, Miri
    Katz, Lior
    Picard, Orit
    Fudim, Ella
    Chowers, Yehuda
    Lang, Alon
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2010, 8 (05) : 475 - 476
  • [4] Case Report: Fatal case of disseminated BCG infection in an infant born to a mother taking infliximab for Crohn's Disease
    Cheent, Kuldeep
    Nolan, Jonathan
    Shariq, Sohail
    Kiho, Liina
    Pal, Arabinda
    Arnold, Jayantha
    [J]. JOURNAL OF CROHNS & COLITIS, 2010, 4 (05) : 603 - 605
  • [5] de Lima A, 2015, GUT
  • [6] Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease
    Jharap, Bindia
    de Boer, Nanne K. H.
    Stokkers, Pieter
    Hommes, Daniel W.
    Oldenburg, Bas
    Dijkstra, Gerard
    van der Woude, C. Janneke
    de Jong, Dirk J.
    Mulder, Chris J. J.
    van Elburg, Ruurd M.
    van Bodegraven, Adriaan A.
    [J]. GUT, 2014, 63 (03) : 451 - 457
  • [7] Anti-TNF Cord Levels Are Significantly Higher After IFX Exposure During Pregnancy Compared to ADA Exposure
    Kanis, Shannon L.
    de Lima, Alison
    van der Ent, Cokkie
    Van der Woude, Christien Janneke
    [J]. GASTROENTEROLOGY, 2016, 150 (04) : S410 - S410
  • [8] Placental Transfer of Anti-Tumor Necrosis Factor Agents in Pregnant Patients With Inflammatory Bowel Disease
    Mahadevan, Uma
    Wolf, Douglas C.
    Dubinsky, Marla
    Cortot, Antoine
    Lee, Scott D.
    Siegel, Corey A.
    Ullman, Thomas
    Glover, Sarah
    Valentine, John F.
    Rubin, David T.
    Miller, Jocelyn
    Abreu, Maria T.
    [J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2013, 11 (03) : 286 - 292
  • [9] The Toronto Consensus Statements for the Management of Inflammatory Bowel Disease in Pregnancy
    Nguyen, Geoffrey C.
    Seow, Cynthia H.
    Maxwell, Cynthia
    Huang, Vivian
    Leung, Yvette
    Jones, Jennifer
    Leontiadis, Grigorios I.
    Tse, Frances
    Mahadevan, Uma
    van der Woude, C. Janneke
    [J]. GASTROENTEROLOGY, 2016, 150 (03) : 734 - +
  • [10] The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease
    van der Woude, C. J.
    Ardizzone, S.
    Bengtson, M. B.
    Fiorino, G.
    Fraser, G.
    Katsanos, K.
    Kolacek, S.
    Juillerat, P.
    Mulders, A. G. M. G. J.
    Pedersen, N.
    Selinger, C.
    Sebastian, S.
    Sturm, A.
    Zelinkova, Z.
    Magro, F.
    [J]. JOURNAL OF CROHNS & COLITIS, 2015, 9 (02) : 107 - 124