Comparative Biomechanics of Thick Filaments and Thin Filaments with Functional Consequences for Muscle Contraction

被引：11

作者：

Miller, Mark S. ^{[1
]}

Tanner, Bertrand C. W. ^{[1
]}

Nyland, Lori R. ^{[1
]}

Vigoreaux, Jim O. ^{[1
,2
]}

机构：

[1] Univ Vermont, Dept Mol Physiol & Biophys, Burlington, VT 05405 USA

[2] Univ Vermont, Dept Biol, Burlington, VT 05405 USA

来源：

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY | 2010年

基金：

美国国家科学基金会;

关键词：

BINDING-PROTEIN-C; INDIRECT FLIGHT-MUSCLE; REGULATORY UNIT INTERACTIONS; SCANNING FORCE MICROSCOPY; SINGLE ACTIN-FILAMENTS; SARCOMERIC M-BAND; S2 HINGE REGIONS; SKELETAL-MUSCLE; INSECT FLIGHT; THERMAL FLUCTUATIONS;

D O I：

10.1155/2010/473423

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The scaffold of striated muscle is predominantly comprised of myosin and actin polymers known as thick filaments and thin filaments, respectively. The roles these filaments play in muscle contraction are well known, but the extent to which variations in filament mechanical properties influence muscle function is not fully understood. Here we review information on the material properties of thick filaments, thin filaments, and their primary constituents; we also discuss ways in which mechanical properties of filaments impact muscle performance.

引用

页数：14

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