The impact of replacement therapy on dental health in haemophilia

被引:1
作者
Kozma, Andrei [1 ,10 ,11 ]
Clevet, Oana [2 ]
Traila, Adina [2 ]
Ursu, Emilia [3 ]
Jinca, Cristian [4 ]
Oancea, Roxana [4 ]
Boeriu, Estera [4 ]
Boia, Eugeniu [4 ]
Ritli, Ladislau [5 ]
Serban, Margit [3 ]
Lackner, Agnes Katherine [6 ]
Lazarescu, Horia [7 ]
Popovici, Calin [1 ]
Diac, Iulia [8 ]
Stanescu, Ana Maria Alexandra [9 ]
Enachescu, C. I. [12 ]
Arghirescu, Smaranda [4 ]
机构
[1] Alessandrescu Rusescu Natl Inst Mother & Child Hl, Res Dept Social Paediat & Obstet, Bucharest, Romania
[2] C Serban Rehabil Med Ctr Children & Adolescents, European Haemophilia Treatment Ctr, Buzias, Romania
[3] Louis Turcanu Children Emergency Hosp, European Haemophilia Treatment Ctr, Timisoara, Romania
[4] Victor Babes Univ Med & Pharm, Timisoara, Romania
[5] Univ Med & Pharm, Oradea, Romania
[6] Med Univ Vienna, Univ Dent Clin, Dept Paediat Dent, Vienna, Austria
[7] Natl Inst Recovery Phys Med & Balneoclimathol, Bucharest, Romania
[8] Carol Davila Univ Med & Pharm, Fac Med, Dept Legal Med & Bioeth, Bucharest, Romania
[9] Carol Davila Univ Med & Pharm, Fac Med, Dept Family Med, Bucharest, Romania
[10] Romanian Acad Med Sci, Bucharest, Romania
[11] Acad Romanian Scientists, Bucharest, Romania
[12] Elias Hosp, Bucharest, Romania
来源
ROMANIAN JOURNAL OF LEGAL MEDICINE | 2019年 / 27卷 / 02期
关键词
pharmacologic replacement therapy; coagulation factor VIII and IX concentrates; haemophilia; dental health; DMFT index; PLI index; CHILDREN; HISTORY;
D O I
10.4323/rjlm.2019.200
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Aim. To evaluate the dental health status and its relationship with the replacement therapy in persons with haemophilia (PwH). Material and methods. In this descriptive non-interventional cross-sectional study we included a number of 47 patients, divided in 2 distinct age groups: 12 patients under- and 35 above 18 years of age. Demographic information, laboratory findings and dental health status were recorded in a standard form. Dental health was evaluated by means of the decay -missing- filling teeth (DMFT) index and plaque index (PLI); these parameters were correlated with the quality of replacement therapy and compared to a matched control group. Results and discussions. The image offered by our descriptive cross-sectional study revealed a dental status in hemophilic children comparable with that of the children from the matched control group. On the contrary, adult PwH have a dismal DMFT and PLI indexes; they are in significant correlations with the quantity and frequency of replaced coagulation factors. Conclusions. The findings highlight the need of comprehensive oral examinations including preventive dental treatment and follow-up care in the PwH connected to an adequate replacement therapy.
引用
收藏
页码:200 / 204
页数:5
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