Proteomics approaches to elucidation of signal transduction pathways

被引：0
|
作者：
Godovac-Zimmermann, J [1 ]
Brown, LR [1 ]
机构：
[1] UCL, Dept Med, Ctr Mol Med, London WC1E 6JJ, England
来源：
CURRENT OPINION IN MOLECULAR THERAPEUTICS | 2003年 / 5卷 / 03期
关键词：
gene expression; post-translational modifications; protein complexes; proteomics; signaling;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Recent applications have shown that proteomics can provide crucial new information regarding cellular signaling processes. Bottom-up and small-scale top-down proteomics approaches related to routine biochemical methods have become widely applied to identify new aspects of established signaling pathways. Top-down, global proteomics methods are developing rapidly and are beginning to deliver information on global integration of signaling processes that has been difficult to obtain with conventional approaches.
引用
收藏
页码：241 / 249
页数：9
相关论文
共 50 条
  • [31] Functional proteomics of signal transduction by membrane receptors
    Godovac-Zimmermann, J
    Soskic, V
    Poznanovic, S
    Brianza, F
    ELECTROPHORESIS, 1999, 20 (4-5) : 952 - 961
  • [32] Proteomics and signal transduction in the crustacean molting gland
    Mykles, DL
    INTEGRATIVE AND COMPARATIVE BIOLOGY, 2005, 45 (06) : 1049 - 1049
  • [33] Proteomics and signal transduction in the crustacean molting gland
    Lee, Sung Gu
    Mykles, Donald L.
    INTEGRATIVE AND COMPARATIVE BIOLOGY, 2006, 46 (06) : 965 - 977
  • [34] Approaches to define antigen receptor-induced serine kinase signal transduction pathways
    Astoul, E
    Laurence, AD
    Totty, N
    Beer, S
    Alexander, DR
    Cantrell, DA
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (11) : 9267 - 9275
  • [35] Treatment of lymphomas via regulating the Signal transduction pathways by natural therapeutic approaches: A review
    Batool, Ammara
    Hazafa, Abu
    Ahmad, Saeed
    Khan, Hamid Ali
    Abideen, Hafiz M. Z.
    Zafar, Ayesha
    Bilal, Muhammad
    Iqbal, Hafiz M. N.
    LEUKEMIA RESEARCH, 2021, 104
  • [36] Interleukin 24: Signal Transduction Pathways
    Smith, Simira
    Lopez, Sual
    Kim, Anastassiya
    Kasteri, Justina
    Olumuyide, Ezekiel
    Punu, Kristian
    de la Parra, Columba
    Sauane, Moira
    CANCERS, 2023, 15 (13)
  • [37] Parameter estimate of signal transduction pathways
    Arisi, Ivan
    Cattaneo, Antonino
    Rosato, Vittorio
    BMC NEUROSCIENCE, 2006, 7 (Suppl 1)
  • [38] Apoptotic signal transduction pathways in diabetes
    Mandrup-Poulsen, T
    BIOCHEMICAL PHARMACOLOGY, 2003, 66 (08) : 1433 - 1440
  • [39] Intersection of signal transduction pathways and development
    Vivekanand, Pavithra
    Rebay, Ilaria
    ANNUAL REVIEW OF GENETICS, 2006, 40 : 139 - 157
  • [40] TRANSMEMBRANE SIGNAL TRANSDUCTION PATHWAYS IN DICTYOSTELIUM
    VANHAASTERT, PJM
    ADVANCES IN SECOND MESSENGER AND PHOSPHOPROTEIN RESEARCH, 1991, 23 : 185 - 226
12345