Proteomics approaches to elucidation of signal transduction pathways

被引：0
|
作者：
Godovac-Zimmermann, J [1 ]
Brown, LR [1 ]
机构：
[1] UCL, Dept Med, Ctr Mol Med, London WC1E 6JJ, England
来源：
CURRENT OPINION IN MOLECULAR THERAPEUTICS | 2003年 / 5卷 / 03期
关键词：
gene expression; post-translational modifications; protein complexes; proteomics; signaling;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Recent applications have shown that proteomics can provide crucial new information regarding cellular signaling processes. Bottom-up and small-scale top-down proteomics approaches related to routine biochemical methods have become widely applied to identify new aspects of established signaling pathways. Top-down, global proteomics methods are developing rapidly and are beginning to deliver information on global integration of signaling processes that has been difficult to obtain with conventional approaches.
引用
收藏
页码：241 / 249
页数：9
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