Mass-sensitive detection of cells, viruses and enzymes with artificial receptors

被引:74
作者
Hayden, O [1 ]
Bindeus, R [1 ]
Haderspöck, C [1 ]
Mann, KJ [1 ]
Wirl, B [1 ]
Dickert, FL [1 ]
机构
[1] Univ Vienna, Inst Analyt Chem, A-1090 Vienna, Austria
来源
SENSORS AND ACTUATORS B-CHEMICAL | 2003年 / 91卷 / 1-3期
基金
奥地利科学基金会;
关键词
quartz crystal microbalance; molecular imprinting; cell; virus; enzyme; crystallization;
D O I
10.1016/S0925-4005(03)00093-5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Synthetic polymer receptors for the online monitoring of bioanalytes are formed directly onto quartz crystal microbalances using surface imprinting techniques. The molded materials are capable of enriching whole cells, viruses and enzymes on the sensor layer surface. Enzyme imprinted polymer layers are also effective as nucleation site for the induction of protein crystallization. Differential measurements are done with a single piezocrystal having two screen-printed gold electrodes for a sensitive and a reference channel. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:316 / 319
页数:4
相关论文
共 19 条
  • [1] Methodology for detection and typing of foodborne microorganisms
    de Boer, E
    Beumer, RR
    [J]. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 1999, 50 (1-2) : 119 - 130
  • [2] Molecularly imprinted polymers for optochemical sensors
    Dickert, FL
    Thierer, S
    [J]. ADVANCED MATERIALS, 1996, 8 (12) : 987 - 990
  • [3] Dickert FL, 2000, ADV MATER, V12, P311, DOI 10.1002/(SICI)1521-4095(200002)12:4<311::AID-ADMA311>3.0.CO
  • [4] 2-G
  • [5] Synthetic receptors as sensor coatings for molecules and living cells
    Dickert, FL
    Hayden, O
    Halikias, KP
    [J]. ANALYST, 2001, 126 (06) : 766 - 771
  • [6] Dickert FL, 1998, ADV MATER, V10, P149, DOI 10.1002/(SICI)1521-4095(199801)10:2<149::AID-ADMA149>3.0.CO
  • [7] 2-2
  • [8] Bioimprinting of polymers and sol-gel phases. Selective detection of yeasts with imprinted polymers
    Dickert, FL
    Hayden, O
    [J]. ANALYTICAL CHEMISTRY, 2002, 74 (06) : 1302 - 1306
  • [9] Sensors based on fingerprints of neutral and ionic analytes in polymeric materials
    Dickert, FL
    Halikias, K
    Hayden, O
    Piu, L
    Sikorski, R
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2001, 76 (1-3): : 295 - 298
  • [10] PREPARATION AND CHEMICAL CHARACTERISTICS OF HEMOGLOBIN-FREE GHOSTS OF HUMAN ERYTHROCYTES
    DODGE, JT
    HANAHAN, DJ
    MITCHELL, C
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1963, 100 (01) : 119 - &