Studying the coagulopathy of COVID-19

被引：23

作者：

Spyropoulos, Alex C. ^{[1
,2
,3
,4
]}

Bonaca, Marc P. ^{[5
,6
]}

机构：

[1] Feinstein Inst Med Res, Inst Hlth Syst Sci, Manhasset, NY 11030 USA

[2] Donald & Barbara Zucker Sch Med Hofstra & Northwe, Hempstead, NY 11549 USA

[3] Lenox Hill Hosp, Dept Med, Anticoagulat & Clin Thrombosis Serv, Northwell Hlth, New York, NY 10075 USA

[4] IM Sechenov First Moscow State Med Univ, Dept Obstet & Gynecol, Moscow, Russia

[5] Univ Colorado, Div Cardiol, Dept Med, Anschutz Med Campus, Aurora, CO USA

[6] CPC Clin Res, Aurora, CO USA

来源：

LANCET | 2022年 / 399卷 / 10320期

关键词：

ANTICOAGULATION;

D O I：

10.1016/S0140-6736(21)01906-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：118 / 119

页数：2

共 12 条

[1]

Berger JS, 2021, LANCET, V397, P2226, DOI 10.1016/S0140-6736(21)01291-5

[2] Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research [J].

Bikdeli, Behnood ;

Madhavan, Mahesh V. ;

Gupta, Aakriti ;

Jimenez, David ;

Burton, John R. ;

Nigoghossian, Caroline Der ;

Chuich, Taylor ;

Nouri, Shayan Nabavi ;

Dreyfus, Isaac ;

Driggin, Elissa ;

Sethi, Sanjum ;

Sehgal, Kartik ;

Chatterjee, Saurav ;

Ageno, Walter ;

Madjid, Mohammad ;

Guo, Yutao ;

Tang, Liang V. ;

Hu, Yu ;

Bertoletti, Laurent ;

Giri, Jay ;

Cushman, Mary ;

Quere, Isabelle ;

Dimakakos, Evangelos P. ;

Gibson, C. Michael ;

Lippi, Giuseppe ;

Favaloro, Emmanuel J. ;

Fareed, Jawed ;

Tafur, Alfonso J. ;

Francese, Dominic P. ;

Batra, Jaya ;

Falanga, Anna ;

Clerkin, Kevin J. ;

Uriel, Nir ;

Kirtane, Ajay ;

McLintock, Claire ;

Hunt, Beverley J. ;

Spyropoulos, Alex C. ;

Barnes, Geoffrey D. ;

Eikelboom, John W. ;

Weinberg, Ido ;

Schulman, Sam ;

Carrier, Marc ;

Piazza, Gregory ;

Beckman, Joshua A. ;

Leon, Martin B. ;

Stone, Gregg W. ;

Rosenkranz, Stephan ;

Goldhaber, Samuel Z. ;

Parikh, Sahil A. ;

Monreal, Manuel .

THROMBOSIS AND HAEMOSTASIS, 2020, 120 (07) :1004-1024

[3] COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow [J].

Bikdeli, Behnood ;

Madhavan, Mahesh V. ;

Jimenez, David ;

Chuich, Taylor ;

Dreyfus, Isaac ;

Driggin, Elissa ;

Der Nigoghossian, Caroline ;

Ageno, Walter ;

Madjid, Mohammad ;

Guo, Yutao ;

Tang, Liang V. ;

Hu, Yu ;

Giri, Jay ;

Cushman, Mary ;

Quere, Isabelle ;

Dimakakos, Evangelos P. ;

Gibson, C. Michael ;

Lippi, Giuseppe ;

Favaloro, Emmanuel J. ;

Fareed, Jawed ;

Caprini, Joseph A. ;

Tafur, Alfonso J. ;

Burton, John R. ;

Francese, Dominic P. ;

Wang, Elizabeth Y. ;

Falanga, Anna ;

McLintock, Claire ;

Hunt, Beverley J. ;

Spyropoulos, Alex C. ;

Barnes, Geoffrey D. ;

Eikelboom, John W. ;

Weinberg, Ido ;

Schulman, Sam ;

Carrier, Marc ;

Piazza, Gregory ;

Beckman, Joshua A. ;

Steg, Gabriel ;

Stone, Gregg W. ;

Rosenkranz, Stephan ;

Goldhaber, Samuel Z. ;

Parikh, Sahil A. ;

Monreal, Manuel ;

Krumholz, Harlan M. ;

Konstantinides, Stavros V. ;

Weitz, Jeffrey I. ;

Lip, Gregory Y. H. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (23) :2950-2973

[4] Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial [J].

Horby, Peter W. ;

Landray, Martin J. .

LANCET, 2021, 397 (10289) :2049-2059

[5] Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial [J].

Lopes, Renato D. ;

de Barros E Silva, Pedro Gabriel Melo ;

Furtado, Remo H. M. ;

Scarlatelli Macedo, Ariane Vieira ;

Bronhara, Bruna ;

Damiani, Lucas Petri ;

Barbosa, Lilian Mazza ;

Morata, Julia de Aveiro ;

Ramacciotti, Eduardo ;

Martins, Priscilla de Aquino ;

de Oliveira, Aryadne Lyrio ;

Nunes, Vinicius Santana ;

Fonteles Ritt, Luiz Eduardo ;

Rocha, Ana Thereza ;

Tramujas, Lucas ;

Santos, Sueli, V ;

Abregu Diaz, Dario Rafael ;

Viana, Lorena Souza ;

Garcia Melro, Livia Maria ;

de Alcantara Chaud, Mariana Silveira ;

Figueiredo, Estevao Lanna ;

Neuenschwander, Fernando Carvalho ;

Andrade Dracoulakis, Marianna Deway ;

Souza Dourado Lima, Rodolfo Godinho ;

de Souza Dantas, Vicente Ces ;

Silva Fernandes, Anne Cristine ;

Eluf Gebara, Otavio Celso ;

Hernandes, Mauro Esteves ;

Rios Queiroz, Diego Aparecido ;

Veiga, Viviane C. ;

Canesin, Manoel Fernandes ;

de Faria, Leonardo Meira ;

Feitosa-Filho, Gilson Soares ;

Gazzana, Marcelo Basso ;

Liporace, Idelzuita Leandro ;

Twardowsky, Aline de Oliveira ;

Maia, Lilia Nigro ;

Machado, Flavia Ribeiro ;

Soeiro, Alexandre de Matos ;

Conceicao-Souza, Germano Emilio ;

Armaganijan, Luciana ;

Guimaraes, Patricia O. ;

Rosa, Regis G. ;

Azevedo, Luciano C. P. ;

Alexander, John H. ;

Avezum, Alvaro ;

Cavalcanti, Alexandre B. ;

Berwanger, Otavio .

LANCET, 2021, 397 (10291) :2253-2263

[6]

O'Brien J, 2000, LANCET, V355, P1295

[7] Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit The INSPIRATION Randomized Clinical Trial [J].

Sadeghipour, Parham ;

Talasaz, Azita H. ;

Rashidi, Farid ;

Sharif-Kashani, Babak ;

Beigmohammadi, Mohammad Taghi ;

Farrokhpour, Mohsen ;

Sezavar, Seyed Hashem ;

Payandemehr, Pooya ;

Dabbagh, Ali ;

Moghadam, Keivan Gohari ;

Jamalkhani, Sepehr ;

Khalili, Hossein ;

Yadollahzadeh, Mahdi ;

Riahi, Taghi ;

Rezaeifar, Parisa ;

Tahamtan, Ouria ;

Matin, Samira ;

Abedini, Atefeh ;

Lookzadeh, Somayeh ;

Rahmani, Hamid ;

Zoghi, Elnaz ;

Mohammadi, Keyhan ;

Sadeghipour, Pardis ;

Abri, Homa ;

Tabrizi, Sanaz ;

Mousavian, Seyed Masoud ;

Shahmirzaei, Shaghayegh ;

Bakhshandeh, Hooman ;

Amin, Ahmad ;

Rafiee, Farnaz ;

Baghizadeh, Elahe ;

Mohebbi, Bahram ;

Parhizgar, Seyed Ehsan ;

Aliannejad, Rasoul ;

Eslami, Vahid ;

Kashefizadeh, Alireza ;

Kakavand, Hessam ;

Hosseini, Seyed Hossein ;

Shafaghi, Shadi ;

Ghazi, Samrand Fattah ;

Najafi, Atabak ;

Jimenez, David ;

Gupta, Aakriti ;

Madhavan, Mahesh V. ;

Sethi, Sanjum S. ;

Parikh, Sahil A. ;

Monreal, Manuel ;

Hadavand, Naser ;

Hajighasemi, Alireza ;

Maleki, Majid .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 325 (16) :1620-1630

[8] Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19 The HEP-COVID Randomized Clinical Trial [J].

Spyropoulos, Alex C. ;

Goldin, Mark ;

Giannis, Dimitrios ;

Diab, Wassim ;

Wang, Janice ;

Khanijo, Sameer ;

Mignatti, Andrea ;

Gianos, Eugenia ;

Cohen, Marc ;

Sharifova, Gulru ;

Lund, Jeet M. ;

Tafur, Alfonso ;

Lewis, Paul A. ;

Cohoon, Kevin P. ;

Rahman, Husneara ;

Sison, Cristina P. ;

Lesser, Martin L. ;

Ochani, Kanta ;

Agrawal, Nirav ;

Hsia, Judith ;

Anderson, Victoria E. ;

Bonaca, Marc ;

Halperin, Jonathan L. ;

Weitz, Jeffrey, I .

JAMA INTERNAL MEDICINE, 2021, 181 (12) :1612-1620

[9] Hospitalized COVID-19 Patients and Venous Thromboembolism A Perfect Storm [J].

Spyropoulos, Alex C. ;

Weitz, Jeffrey I. .

CIRCULATION, 2020, 142 (02) :129-132

[10] Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration [J].

Tritschler, Tobias ;

Mathieu, Marie-Eve ;

Skeith, Leslie ;

Rodger, Marc ;

Middeldorp, Saskia ;

Brighton, Timothy ;

Sandset, Per Morten ;

Kahn, Susan R. ;

Angus, Derek C. ;

Blondon, Marc ;

Bonten, Marc J. ;

Cattaneo, Marco ;

Cushman, Mary ;

Derde, Lennie P. G. ;

DeSancho, Maria T. ;

Diehl, Jean-Luc ;

Goligher, Ewan ;

Jilma, Bernd ;

Juni, Peter ;

Lawler, Patrick R. ;

Marietta, Marco ;

Marshall, John C. ;

McArthur, Colin ;

Miranda, Carlos Henrique ;

Mirault, Tristan ;

Morici, Nuccia ;

Perepu, Usha ;

Schoergenhofer, Christian ;

Sholzberg, Michelle ;

Spyropoulos, Alex C. ;

Webb, Steve A. ;

Zarychanski, Ryan ;

Zuily, Stephane ;

Le Gal, Gregoire .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 18 (11) :2958-2967

← 1 2 →

共 12 条

[1]

Berger JS, 2021, LANCET, V397, P2226, DOI 10.1016/S0140-6736(21)01291-5

[2] Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research [J].

Bikdeli, Behnood ;

Madhavan, Mahesh V. ;

Gupta, Aakriti ;

Jimenez, David ;

Burton, John R. ;

Nigoghossian, Caroline Der ;

Chuich, Taylor ;

Nouri, Shayan Nabavi ;

Dreyfus, Isaac ;

Driggin, Elissa ;

Sethi, Sanjum ;

Sehgal, Kartik ;

Chatterjee, Saurav ;

Ageno, Walter ;

Madjid, Mohammad ;

Guo, Yutao ;

Tang, Liang V. ;

Hu, Yu ;

Bertoletti, Laurent ;

Giri, Jay ;

Cushman, Mary ;

Quere, Isabelle ;

Dimakakos, Evangelos P. ;

Gibson, C. Michael ;

Lippi, Giuseppe ;

Favaloro, Emmanuel J. ;

Fareed, Jawed ;

Tafur, Alfonso J. ;

Francese, Dominic P. ;

Batra, Jaya ;

Falanga, Anna ;

Clerkin, Kevin J. ;

Uriel, Nir ;

Kirtane, Ajay ;

McLintock, Claire ;

Hunt, Beverley J. ;

Spyropoulos, Alex C. ;

Barnes, Geoffrey D. ;

Eikelboom, John W. ;

Weinberg, Ido ;

Schulman, Sam ;

Carrier, Marc ;

Piazza, Gregory ;

Beckman, Joshua A. ;

Leon, Martin B. ;

Stone, Gregg W. ;

Rosenkranz, Stephan ;

Goldhaber, Samuel Z. ;

Parikh, Sahil A. ;

Monreal, Manuel .

THROMBOSIS AND HAEMOSTASIS, 2020, 120 (07) :1004-1024

[3] COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow [J].

Bikdeli, Behnood ;

Madhavan, Mahesh V. ;

Jimenez, David ;

Chuich, Taylor ;

Dreyfus, Isaac ;

Driggin, Elissa ;

Der Nigoghossian, Caroline ;

Ageno, Walter ;

Madjid, Mohammad ;

Guo, Yutao ;

Tang, Liang V. ;

Hu, Yu ;

Giri, Jay ;

Cushman, Mary ;

Quere, Isabelle ;

Dimakakos, Evangelos P. ;

Gibson, C. Michael ;

Lippi, Giuseppe ;

Favaloro, Emmanuel J. ;

Fareed, Jawed ;

Caprini, Joseph A. ;

Tafur, Alfonso J. ;

Burton, John R. ;

Francese, Dominic P. ;

Wang, Elizabeth Y. ;

Falanga, Anna ;

McLintock, Claire ;

Hunt, Beverley J. ;

Spyropoulos, Alex C. ;

Barnes, Geoffrey D. ;

Eikelboom, John W. ;

Weinberg, Ido ;

Schulman, Sam ;

Carrier, Marc ;

Piazza, Gregory ;

Beckman, Joshua A. ;

Steg, Gabriel ;

Stone, Gregg W. ;

Rosenkranz, Stephan ;

Goldhaber, Samuel Z. ;

Parikh, Sahil A. ;

Monreal, Manuel ;

Krumholz, Harlan M. ;

Konstantinides, Stavros V. ;

Weitz, Jeffrey I. ;

Lip, Gregory Y. H. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (23) :2950-2973

[4] Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial [J].

Horby, Peter W. ;

Landray, Martin J. .

LANCET, 2021, 397 (10289) :2049-2059

Lopes, Renato D. ;

de Barros E Silva, Pedro Gabriel Melo ;

Furtado, Remo H. M. ;

Scarlatelli Macedo, Ariane Vieira ;

Bronhara, Bruna ;

Damiani, Lucas Petri ;

Barbosa, Lilian Mazza ;

Morata, Julia de Aveiro ;

Ramacciotti, Eduardo ;

Martins, Priscilla de Aquino ;

de Oliveira, Aryadne Lyrio ;

Nunes, Vinicius Santana ;

Fonteles Ritt, Luiz Eduardo ;

Rocha, Ana Thereza ;

Tramujas, Lucas ;

Santos, Sueli, V ;

Abregu Diaz, Dario Rafael ;

Viana, Lorena Souza ;

Garcia Melro, Livia Maria ;

de Alcantara Chaud, Mariana Silveira ;

Figueiredo, Estevao Lanna ;

Neuenschwander, Fernando Carvalho ;

Andrade Dracoulakis, Marianna Deway ;

Souza Dourado Lima, Rodolfo Godinho ;

de Souza Dantas, Vicente Ces ;

Silva Fernandes, Anne Cristine ;

Eluf Gebara, Otavio Celso ;

Hernandes, Mauro Esteves ;

Rios Queiroz, Diego Aparecido ;

Veiga, Viviane C. ;

Canesin, Manoel Fernandes ;

de Faria, Leonardo Meira ;

Feitosa-Filho, Gilson Soares ;

Gazzana, Marcelo Basso ;

Liporace, Idelzuita Leandro ;

Twardowsky, Aline de Oliveira ;

Maia, Lilia Nigro ;

Machado, Flavia Ribeiro ;

Soeiro, Alexandre de Matos ;

Conceicao-Souza, Germano Emilio ;

Armaganijan, Luciana ;

Guimaraes, Patricia O. ;

Rosa, Regis G. ;

Azevedo, Luciano C. P. ;

Alexander, John H. ;

Avezum, Alvaro ;

Cavalcanti, Alexandre B. ;

Berwanger, Otavio .

LANCET, 2021, 397 (10291) :2253-2263

[6]

O'Brien J, 2000, LANCET, V355, P1295

Sadeghipour, Parham ;

Talasaz, Azita H. ;

Rashidi, Farid ;

Sharif-Kashani, Babak ;

Beigmohammadi, Mohammad Taghi ;

Farrokhpour, Mohsen ;

Sezavar, Seyed Hashem ;

Payandemehr, Pooya ;

Dabbagh, Ali ;

Moghadam, Keivan Gohari ;

Jamalkhani, Sepehr ;

Khalili, Hossein ;

Yadollahzadeh, Mahdi ;

Riahi, Taghi ;

Rezaeifar, Parisa ;

Tahamtan, Ouria ;

Matin, Samira ;

Abedini, Atefeh ;

Lookzadeh, Somayeh ;

Rahmani, Hamid ;

Zoghi, Elnaz ;

Mohammadi, Keyhan ;

Sadeghipour, Pardis ;

Abri, Homa ;

Tabrizi, Sanaz ;

Mousavian, Seyed Masoud ;

Shahmirzaei, Shaghayegh ;

Bakhshandeh, Hooman ;

Amin, Ahmad ;

Rafiee, Farnaz ;

Baghizadeh, Elahe ;

Mohebbi, Bahram ;

Parhizgar, Seyed Ehsan ;

Aliannejad, Rasoul ;

Eslami, Vahid ;

Kashefizadeh, Alireza ;

Kakavand, Hessam ;

Hosseini, Seyed Hossein ;

Shafaghi, Shadi ;

Ghazi, Samrand Fattah ;

Najafi, Atabak ;

Jimenez, David ;

Gupta, Aakriti ;

Madhavan, Mahesh V. ;

Sethi, Sanjum S. ;

Parikh, Sahil A. ;

Monreal, Manuel ;

Hadavand, Naser ;

Hajighasemi, Alireza ;

Maleki, Majid .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2021, 325 (16) :1620-1630

Spyropoulos, Alex C. ;

Goldin, Mark ;

Giannis, Dimitrios ;

Diab, Wassim ;

Wang, Janice ;

Khanijo, Sameer ;

Mignatti, Andrea ;

Gianos, Eugenia ;

Cohen, Marc ;

Sharifova, Gulru ;

Lund, Jeet M. ;

Tafur, Alfonso ;

Lewis, Paul A. ;

Cohoon, Kevin P. ;

Rahman, Husneara ;

Sison, Cristina P. ;

Lesser, Martin L. ;

Ochani, Kanta ;

Agrawal, Nirav ;

Hsia, Judith ;

Anderson, Victoria E. ;

Bonaca, Marc ;

Halperin, Jonathan L. ;

Weitz, Jeffrey, I .

JAMA INTERNAL MEDICINE, 2021, 181 (12) :1612-1620

[9] Hospitalized COVID-19 Patients and Venous Thromboembolism A Perfect Storm [J].

Spyropoulos, Alex C. ;

Weitz, Jeffrey I. .

CIRCULATION, 2020, 142 (02) :129-132

[10] Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration [J].

Tritschler, Tobias ;

Mathieu, Marie-Eve ;

Skeith, Leslie ;

Rodger, Marc ;

Middeldorp, Saskia ;

Brighton, Timothy ;

Sandset, Per Morten ;

Kahn, Susan R. ;

Angus, Derek C. ;

Blondon, Marc ;

Bonten, Marc J. ;

Cattaneo, Marco ;

Cushman, Mary ;

Derde, Lennie P. G. ;

DeSancho, Maria T. ;

Diehl, Jean-Luc ;

Goligher, Ewan ;

Jilma, Bernd ;

Juni, Peter ;

Lawler, Patrick R. ;

Marietta, Marco ;

Marshall, John C. ;

McArthur, Colin ;

Miranda, Carlos Henrique ;

Mirault, Tristan ;

Morici, Nuccia ;

Perepu, Usha ;

Schoergenhofer, Christian ;

Sholzberg, Michelle ;

Spyropoulos, Alex C. ;

Webb, Steve A. ;

Zarychanski, Ryan ;

Zuily, Stephane ;

Le Gal, Gregoire .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 18 (11) :2958-2967

← 1 2 →